AANAT Produkte
(Aralkylamine N-Acetyltransferase (AANAT))
Kategorien
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
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Ausgewählte AANAT Kategorien
AANAT Antikörper
High quality antibodies with extensive validation data.
AANAT ELISA Kits
Reliable ELISA kits for a wide range of species.
AANAT Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene AANAT Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat, Sheep
Applikation
ELISA, WB, IF (cc), IF (p), IHC (fro), IHC (p)
Validierungen
- (2)
- (6)
Kat. Nr.
ABIN751063
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, ICC, IP
Validierungen
- (2)
Kat. Nr.
ABIN7444538
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB, IF
Validierungen
- (2)
Kat. Nr.
ABIN7169324
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene AANAT ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965002
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965001
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6953911
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene AANAT Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1305403
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7395332
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7418458
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren AANAT Produkten
: "Profile of melatonin and its receptors and synthesizing enzymes in cumulus-oocyte complexes of the developing sheep antral follicle-a potential estradiol-mediated mechanism." in: Reproductive biology and endocrinology : RB&E, Vol. 17, Issue 1, pp. 1, (2019) (PubMed).: "Comparison of arylalkylamine N-acetyltransferase and melatonin receptor type 1B immunoreactivity between young adult and aged canine spinal cord." in: Journal of veterinary science, Vol. 15, Issue 3, pp. 335-42, (2016) (PubMed).
: "Arylalkylamine N-acetyltransferase: "the Timezyme"." in: The Journal of biological chemistry, Vol. 282, Issue 7, pp. 4233-7, (2007) (PubMed).
: "14-3-3 proteins in pineal photoneuroendocrine transduction: how many roles?" in: Journal of neuroendocrinology, Vol. 15, Issue 4, pp. 370-7, (2003) (PubMed).
: "Retinal melatonin production: role of proteasomal proteolysis in circadian and photic control of arylalkylamine N-acetyltransferase." in: Investigative ophthalmology & visual science, Vol. 43, Issue 2, pp. 564-72, (2002) (PubMed).
: "14-3-3 Proteins and photoneuroendocrine transduction: role in controlling the daily rhythm in melatonin." in: Biochemical Society transactions, Vol. 30, Issue 4, pp. 365-73, (2002) (PubMed).
: "Melatonin synthesis enzymes in Macaca mulatta: focus on arylalkylamine N-acetyltransferase (EC 2.3.1.87)." in: The Journal of clinical endocrinology and metabolism, Vol. 87, Issue 10, pp. 4699-706, (2002) (PubMed).
: "cAmp regulation of arylalkylamine N-acetyltransferase (AANAT, EC 2.3.1.87): a new cell line (1E7) provides evidence of intracellular AANAT activation." in: The Journal of biological chemistry, Vol. 276, Issue 26, pp. 24097-107, (2001) (PubMed).
Synonyme und alternative Namen zu AANAT
aralkylamine N-acetyltransferase (AANAT), aralkylamine N-acetyltransferase (Aanat), arylalkylamine N-acetyltransferase (Aanat), AA-NAT, DSPS, Nat-2, Nat4, SNAT, SnatBezeichner auf Proteinebene für AANAT
- arylalkylamine N-acetyltransferase
- serotonin N-acetyltransferase
- serotonin acetylase
- Arylalkylamine N - acetyltransferase (Serotonin N - acetyltransferase)
- Seretonin N-acetyltransferase
- arylakylamine N-acetyltransferase
- AA-NAT
- pineal serotonin N-acetyltransferase
- pineal arylalkylamine N-acetyltransferase
- aralkylamine N-acetyltransferase
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