ABCB1 Produkte
(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
Kategorien
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008].
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Ausgewählte ABCB1 Kategorien
ABCB1 Antikörper
High quality antibodies with extensive validation data.
ABCB1 ELISA Kits
Reliable ELISA kits for a wide range of species.
ABCB1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ABCB1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC (p), IHC (fro)
Validierungen
- (30)
- (5)
Kat. Nr.
ABIN3043967
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IHC (p)
Validierungen
- (7)
Kat. Nr.
ABIN1491725
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC
Validierungen
- (5)
Kat. Nr.
ABIN7265732
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene ABCB1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN6965064
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965066
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965065
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ABCB1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1305435
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7121929
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7505266
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ABCB1 Produkten
: "Microphysiological Conditions Do Not Affect MDR1-Mediated Transport of Rhodamine 123 above an Artificial Proximal Tubule." in: Biomedicines, Vol. 11, Issue 7, (2023) (PubMed).: "Association Analysis of Single-Cell RNA Sequencing and Proteomics Reveals a Vital Role of Ca2+ Signaling in the Determination of Skeletal Muscle Development Potential." in: Cells, Vol. 9, Issue 4, (2021) (PubMed).
: "Hypoxia-tropic Protein Nanocages for Modulation of Tumor- and Chemotherapy-Associated Hypoxia." in: ACS nano, Vol. 13, Issue 1, pp. 236-247, (2019) (PubMed).
: "PAMAM dendrimer grafted cellulose paper scaffolds as a novel in vitro 3D liver model for drug screening applications." in: Colloids and surfaces. B, Biointerfaces, Vol. 172, pp. 346-354, (2019) (PubMed).
: "Manganese transporter Slc30a10 controls physiological manganese excretion and toxicity." in: The Journal of clinical investigation, Vol. 129, Issue 12, pp. 5442-5461, (2019) (PubMed).
: "MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition." in: Gene, Vol. 652, pp. 48-58, (2018) (PubMed).
: "Increased autophagy in EOC re-ascites cells can inhibit cell death and promote drug resistance." in: Cell death & disease, Vol. 9, Issue 4, pp. 419, (2018) (PubMed).
: "Brusatol Enhances the Chemotherapy Efficacy of Gemcitabine in Pancreatic Cancer via the Nrf2 Signalling Pathway." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 2360427, (2018) (PubMed).
: "Role of P-glycoprotein inhibitors in children with drug-resistant epilepsy." in: Acta neurologica Scandinavica, Vol. 136, Issue 6, pp. 639-644, (2018) (PubMed).
: "Positive Feedback Loop of OCT4 and c-JUN Expedites Cancer Stemness in Liver Cancer." in: Stem cells (Dayton, Ohio), Vol. 34, Issue 11, pp. 2613-2624, (2018) (PubMed).
Synonyme und alternative Namen zu ABCB1
ATP binding cassette subfamily B member 1 (ABCB1), ATP binding cassette subfamily B member 1A (Abcb1a), ATP binding cassette subfamily B member 1 L homeolog (abcb1.L), ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b), ATP binding cassette subfamily B member 1 (Abcb1), ABC20, Abcb1, ABCB1, CD243, CLCS, GP170, mdr, MDR1, Mdr1, Mdr1a, Mdr1b, P-GP, p-gp, PGP1, Pgy-1, PGY1, Pgy1, xemdrBezeichner auf Proteinebene für ABCB1
- P-glycoprotein 1
- colchicin sensitivity
- doxorubicin resistance
- multidrug resistance protein 1
- ATP-binding cassette, sub-family B (MDR/TAP), member 1
- ATP-binding cassette, subfamily B (MDR/TAP), member 1A
- multiple drug resistant 1a
- bovine P-glycoprotein
- ATP-binding cassette, subfamily B, member 1
- P-glycoprotein
- multidrug resistance p-glycoprotein
- multidrug resistance protein
- ATP-binding cassette sub-family B member 1
- P glycoprotein 1
- multidrug resistance protein 1B
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