ABCC2 Produkte
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2))
Kategorien
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine\; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008].
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Ausgewählte ABCC2 Kategorien
ABCC2 Antikörper
High quality antibodies with extensive validation data.
ABCC2 ELISA Kits
Reliable ELISA kits for a wide range of species.
ABCC2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ABCC2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (5)
Kat. Nr.
ABIN7441076
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p)
Validierungen
- (3)
Kat. Nr.
ABIN737541
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (3)
Kat. Nr.
ABIN514490
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene ABCC2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6953980
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5652070
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ABCC2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1305455
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7407940
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ABCC2 Produkten
: "Stimulatory effect of CSE-generated H2S on hepatic mitochondrial biogenesis and the underlying mechanisms." in: Nitric oxide : biology and chemistry, Vol. 58, pp. 67-76, (2016) (PubMed).: "Modulation of drug-resistant membrane and apoptosis proteins of breast cancer stem cells by targeting berberine liposomes." in: Biomaterials, Vol. 34, Issue 18, pp. 4452-65, (2013) (PubMed).
: "Expression in human endothelial cells of ADP-ribosylation factors, 20-kDa guanine nucleotide-binding proteins involved in the initiation of vesicular transport." in: Journal of molecular and cellular cardiology, Vol. 28, Issue 9, pp. 1911-20, (1997) (PubMed).
: "Isolation of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP ribosylation factor (ARF) 1 and ARF3 that contains a Sec7-like domain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 23, pp. 12856-60, (1996) (PubMed).
: "Phospholipase D: a downstream effector of ARF in granulocytes." in: Science (New York, N.Y.), Vol. 263, Issue 5146, pp. 523-6, (1994) (PubMed).
: "ADP-ribosylation factors, 20,000 M(r) guanine nucleotide-binding protein activators of cholera toxin and components of intracellular vesicular transport systems." in: Cellular signalling, Vol. 5, Issue 4, pp. 367-79, (1993) (PubMed).
: "Purification of a protein cofactor required for ADP-ribosylation of the stimulatory regulatory component of adenylate cyclase by cholera toxin." in: The Journal of biological chemistry, Vol. 259, Issue 10, pp. 6228-34, (1984) (PubMed).
Synonyme und alternative Namen zu ABCC2
ATP binding cassette subfamily C member 2 (ABCC2), ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (Abcc2), ATP binding cassette subfamily C member 2 (Abcc2), ABC30, Abc30, AI173996, CMOAT, Cmoat, cMRP, DJS, MRP2, Mrp2Bezeichner auf Proteinebene für ABCC2
- ATP-binding cassette sub-family C member 2
- canalicular multidrug resistance protein
- canalicular multispecific organic anion transporter 1
- multidrug resistance-associated protein 2
- multidrug resistance protein 2
- ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- calicular multispecific organic anion transporter
- multidrug resistance associated protein 2
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