ABCC5 Produkte
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))
Kategorien
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected\; however, the complete sequence and translation initiation site is unclear. [provided by RefSeq, Jul 2008].
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Ausgewählte ABCC5 Kategorien
ABCC5 Antikörper
High quality antibodies with extensive validation data.
ABCC5 ELISA Kits
Reliable ELISA kits for a wide range of species.
ABCC5 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ABCC5 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (5)
Kat. Nr.
ABIN302162
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN6266184
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7160318
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene ABCC5 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6964517
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6953382
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ABCC5 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1305459
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1305461
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7407949
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ABCC5 Produkten
: "Brusatol Enhances the Chemotherapy Efficacy of Gemcitabine in Pancreatic Cancer via the Nrf2 Signalling Pathway." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 2360427, (2018) (PubMed).: "Effects of chronic renal failure on brain drug transporters in rats." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 1, pp. 39-46, (2011) (PubMed).
: "Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts: effects of gestational age and cellular ..." in: The American journal of pathology, Vol. 166, Issue 1, pp. 39-48, (2005) (PubMed).
Synonyme und alternative Namen zu ABCC5
ATP binding cassette subfamily C member 5 (ABCC5), ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (Abcc5), ATP binding cassette subfamily C member 5 (Abcc5), ATP binding cassette subfamily C member 5 L homeolog (abcc5.L), 2900011L11Rik, ABC33, abc33, abcc5, Abcc5a, Abcc5b, AI132311, EST277145, MOAT-C, moat-c, MOATC, moatc, MRP5, Mrp5, mrp5, pABC11, pabc11, SMRP, smrpBezeichner auf Proteinebene für ABCC5
- ATP-binding cassette sub-family C member 5
- canalicular multispecific organic anion transporter C
- multi-specific organic anion transporter C
- multidrug resistance-associated protein 5
- ATP-binding cassette, sub-family C (CFTR/MRP), member 5a
- ATP-binding cassette, sub-family C (CFTR/MRP), member 5b
- ATP-binding cassette, sub-family C, member 5
- MOAT-C
- SMRP
- ATP-binding cassette sub-family C (CFTR/MRP) member 5a
- ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- ATP binding cassette subfamily C member 5 L homeolog
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