ACE2 Produkte
(Angiotensin I Converting Enzyme 2 (ACE2))
Kategorien
ACE2 short description:
Essential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis (PubMed:27217402). Converts angiotensin I to angiotensin 1-9, a nine-amino acid peptide with anti-hypertrophic effects in cardiomyocytes, and angiotensin II to angiotensin 1-7, which then acts as a beneficial vasodilator and anti-proliferation agent, counterbalancing the actions of the vasoconstrictor angiotensin II (PubMed:10969042, PubMed:10924499, PubMed:11815627, PubMed:19021774, PubMed:14504186). Also removes the C-terminal residue from three other vasoactive peptides, neurotensin, kinetensin, and des-Arg bradykinin, but is not active on bradykinin (PubMed:10969042, PubMed:11815627). Also cleaves other biological peptides, such as apelins (apelin-13, [Pyr1]apelin-13, apelin-17, apelin-36), casomorphins (beta-casomorphin-7, neocasomorphin) and dynorphin A with high efficiency (PubMed:11815627, PubMed:27217402, PubMed:28293165). In addition, ACE2 C-terminus is homologous to collectrin and is responsible for the trafficking of the neutral amino acid transporter SL6A19 to the plasma membrane of gut epithelial cells via direct interaction, regulating its expression on the cell surface and its catalytic activity (PubMed:18424768, PubMed:19185582).Additional Resources:
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Ausgewählte ACE2 Kategorien
ACE2 Antikörper
High quality antibodies with extensive validation data.
ACE2 ELISA Kits
Reliable ELISA kits for a wide range of species.
ACE2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ACE2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, FACS
Validierungen
- (4)
- (5)
Kat. Nr.
ABIN1169449
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Validierungen
- (1)
- (5)
Kat. Nr.
ABIN730798
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (7)
Kat. Nr.
ABIN6136429
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene ACE2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6963302
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6953749
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6964862
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ACE2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
- (7)
Kat. Nr.
ABIN6952431
Menge
200 μg
Datenblatt
Datenblatt
Reaktivität
Paguma larvata
Source
HEK-293 Cells
Validierungen
- (8)
Kat. Nr.
ABIN6952704
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (4)
Kat. Nr.
ABIN7273792
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ACE2 Produkten
: "SARS-CoV-2 receptor binding domain fusion protein efficiently neutralizes virus infection." in: PLoS pathogens, Vol. 17, Issue 12, pp. e1010175, (2022) (PubMed).: "Anti-human ACE2 antibody neutralizes and inhibits virus production of SARS-CoV-2 variants of concern." in: iScience, Vol. 25, Issue 9, pp. 104935, (2022) (PubMed).
: "Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection. ..." in: Cell, Vol. 184, Issue 1, pp. 76-91.e13, (2021) (PubMed).
: "SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination." in: Advanced materials (Deerfield Beach, Fla.), Vol. 32, Issue 50, pp. e2005637, (2021) (PubMed).
: "SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus." in: Communications biology, Vol. 4, Issue 1, pp. 129, (2021) (PubMed).
: "Dromedary camels as a natural source of neutralizing nanobodies against SARS-CoV-2." in: JCI insight, (2021) (PubMed).
: "SARS-CoV-2 D614G spike mutation increases entry efficiency with enhanced ACE2-binding affinity." in: Nature communications, Vol. 12, Issue 1, pp. 848, (2021) (PubMed).
: "Ameliorative effect of AT2R and ACE2 activation on ischemic renal injury associated cardiac and hepatic dysfunction." in: Environmental toxicology and pharmacology, Vol. 80, pp. 103501, (2021) (PubMed).
: "Chicken Egg Yolk Antibodies (IgYs) block the binding of multiple SARS-CoV-2 spike protein variants to human ACE2." in: International immunopharmacology, Vol. 90, pp. 107172, (2021) (PubMed).
: "Neutralizing antibodies targeting the SARS-CoV-2 receptor binding domain isolated from a naïve human antibody library." in: Protein science : a publication of the Protein Society, Vol. 30, Issue 4, pp. 716-727, (2021) (PubMed).
Synonyme und alternative Namen zu ACE2
angiotensin I converting enzyme (ACE), angiotensin I converting enzyme 2 (ACE2), angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (Ace2), angiotensin I converting enzyme 2 (Ace2), angiotensin I converting enzyme 2 (ace2), angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2), 2010305L05Rik, ACE1, ACEH, CD143, DCP, DCP1, ICH, MVCD3, zgc:92514Bezeichner auf Proteinebene für ACE2
- CD143 antigen
- angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
- angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript
- angiotensin converting enzyme, somatic isoform
- angiotensin-converting enzyme
- carboxycathepsin
- dipeptidyl carboxypeptidase 1
- dipeptidyl carboxypeptidase I
- kininase II
- peptidase P
- testicular ECA
- ACE-related carboxypeptidase
- angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
- angiotensin-converting enzyme 2
- angiotensin-converting enzyme homolog
- metalloprotease MPROT15
- peptidyl-dipeptidase A
- angiotensin I converting enzyme 2
- anigotensin-converting enzyme-related carboxypeptidase
- renal angiotensin-converting enzyme 2
Haben Sie etwas anderes gesucht?
- ACD1
- ACD
- ACCSL
- ACCN5
- ACCN4
- ACCN1
- ACCD6
- ACC Synthase 7
- ACBD7
- ACBD6
- ACBD5
- ACBD4
- ACBD3
- ACAT2
- ACAT1
- Acap3
- ACAP1
- ACADVL
- ACADSB
- ACADS
- ACEI
- ACER1
- ACER2
- ACER3
- Acetate Kinase
- Acetoin Reductase
- Acetyl-CoA
- Acetyl-CoA Carboxylase
- Acetyl-CoA Carboxylase alpha
- Acetyl-CoA Carboxylase beta
- Acetylated Lysine
- Acetylcholine
- Acetylcholinesterase
- Achaete
- Achaete-Scute Complex Homolog 1 (Drosophila)
- Achaete-scute complex protein T5
- ACHB3
- AChR Ab
- Acid Invertase
- Acid Phosphatase
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