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Actin-Like 6A Produkte

(Actin-Like 6A (BAF53A))
This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila\; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq, Jul 2008].

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Ausgewählte Actin-Like 6A Kategorien

Actin-Like 6A Antikörper

High quality antibodies with extensive validation data.

Actin-Like 6A ELISA Kits

Reliable ELISA kits for a wide range of species.

Actin-Like 6A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Actin-Like 6A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, ChIP
Validierungen
  • (3)
Kat. Nr. ABIN7143052
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN6243024
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (3)
Kat. Nr. ABIN513096
Menge 100 μg
Datenblatt Datenblatt

Empfohlene Actin-Like 6A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953404
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN5648156
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Actin-Like 6A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7121656
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1305755
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1305757
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Actin-Like 6A Produkten

Gatchalian, Malik, Ho, Lee, Kelso, Shokhirev, Dixon, Hargreaves: "A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells." in: Nature communications, Vol. 9, Issue 1, pp. 5139, (2019) (PubMed).

Miller, Hargreaves, Kadoch, Chang, Calarco, Hodges, Buenrostro, Cui, Greenleaf, Zhao, Crabtree: "TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin." in: Nature structural & molecular biology, Vol. 24, Issue 4, pp. 344-352, (2017) (PubMed).

Bao, Tang, Lopez-Pajares, Tao, Qu, Crabtree, Khavari: "ACTL6a enforces the epidermal progenitor state by suppressing SWI/SNF-dependent induction of KLF4." in: Cell stem cell, Vol. 12, Issue 2, pp. 193-203, (2013) (PubMed).

Staahl, Tang, Wu, Sun, Gitler, Yoo, Crabtree: "Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 25, pp. 10348-61, (2013) (PubMed).

Harata, Mochizuki, Mizuno: "Two isoforms of a human actin-related protein show nuclear localization and mutually selective expression between brain and other tissues." in: Bioscience, biotechnology, and biochemistry, Vol. 63, Issue 5, pp. 917-23, (1999) (PubMed).

Kelso, Porter, Amaral, Shokhirev, Benner, Hargreaves: "Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers." in: eLife, Vol. 6 (PubMed).

Synonyme und alternative Namen zu Actin-Like 6A

actin like 6A (ACTL6A), actin-like 6A (Actl6a), actin-like 6A (actl6a), actin like 6A (actl6a), actin-related protein 4 (ARP4), actin like 6A (Actl6a), Arp4p (ARP4), actin like 6A S homeolog (actl6a.S), 2810432C06Rik, actin, Actin-like protein 4, actin-related protein 4, ACTL6, Actl6, actl6, ACTL6A, actl6a, actl6a.L, AI851094, Arp4, ARP4, arp4, ARPN-BETA, arpn-beta, ATARP4, BAF53A, Baf53a, baf53a, C79802, CaO19.5623, chunp6900, F15H18.8, F15H18_8, fb52e06, fl26e12, INO80K, ino80k, MGC75671, RGD1307747, wu:fb52e06, wu:fl26e12

Bezeichner auf Proteinebene für Actin-Like 6A

  • 53 kDa BRG1-associated factor A
  • BAF complex 53 kDa subunit
  • BAF53
  • BRG1-associated factor 53A
  • INO80 complex subunit K
  • actin-like protein 6A
  • actin-related protein 4
  • actin-related protein Baf53a
  • arpNbeta
  • hArpN beta
  • BRG1/brm-associated factor 53A
  • actin-like 6
  • actin-like 6A
  • etID38198.6
  • actin-like protein 6A-like
  • Actin-like protein ARP4
  • actin like 6A L homeolog
  • actin like 6A S homeolog
  • actin-related protein
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