ACVR1 Produkte
(Activin Receptor Type I (ACRV1))
Kategorien
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq, Jul 2008].
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Ausgewählte ACVR1 Kategorien
ACVR1 Antikörper
High quality antibodies with extensive validation data.
ACVR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
ACVR1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ACVR1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (2)
- (4)
Kat. Nr.
ABIN392240
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN391156
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN657718
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene ACVR1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6953435
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN1742678
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Sheep
Analytical Method
Validierungen
Kat. Nr.
ABIN1773582
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ACVR1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1305799
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1305801
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN7194135
Menge
200 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ACVR1 Produkten
: "Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps." in: Scientific reports, Vol. 8, Issue 1, pp. 1561, (2018) (PubMed).: "Chronic myeloid leukaemia cells require the bone morphogenic protein pathway for cell cycle progression and self-renewal." in: Cell death & disease, Vol. 9, Issue 9, pp. 927, (2018) (PubMed).
: "Establishment of a novel model of chondrogenesis using murine embryonic stem cells carrying fibrodysplasia ossificans progressiva-associated mutant ALK2." in: Biochemical and biophysical research communications, Vol. 455, Issue 3-4, pp. 347-52, (2014) (PubMed).
: "Dysregulation of local stem/progenitor cells as a common cellular mechanism for heterotopic ossification." in: Stem cells (Dayton, Ohio), Vol. 27, Issue 1, pp. 150-6, (2009) (PubMed).
: "BMP7 is a podocyte survival factor and rescues podocytes from diabetic injury." in: American journal of physiology. Renal physiology, Vol. 293, Issue 5, pp. F1641-8, (2007) (PubMed).
: "A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva." in: Nature genetics, Vol. 38, Issue 5, pp. 525-7, (2006) (PubMed).
: "A limited set of human MicroRNA is deregulated in follicular thyroid carcinoma." in: The Journal of clinical endocrinology and metabolism, Vol. 91, Issue 9, pp. 3584-91, (2006) (PubMed).
: "EphB4 provides survival advantage to squamous cell carcinoma of the head and neck." in: International journal of cancer, Vol. 119, Issue 6, pp. 1236-48, (2006) (PubMed).
: "Inhibin, activin, follistatin, activin receptors and beta-glycan gene expression in the placental tissue of patients with pre-eclampsia." in: Molecular human reproduction, Vol. 9, Issue 4, pp. 199-203, (2003) (PubMed).
: "The distribution of activin and activin receptors in gestational tissues across human pregnancy and during labour." in: Placenta, Vol. 23, Issue 4, pp. 294-302, (2002) (PubMed).
Synonyme und alternative Namen zu ACVR1
activin A receptor type 1 (ACVR1), activin A receptor type 1 (Acvr1), activin A receptor, type 1 (Acvr1), activin A receptor type 1 S homeolog (acvr1.S), ActR-I, ActR-IA, ACTRI, actri, ActRIA, Acvr, acvr1, acvr1-a, acvr1-b, ACVR1A, acvr1a, ACVRLK2, Acvrlk2, acvrlk2, Alk-2, alk-2, ALK2, alk2, Alk8, alk8, D330013D15Rik, FOP, fop, sax, SKR1, skr1, Tsk7L, TSRI, tsri, xALK-2Bezeichner auf Proteinebene für ACVR1
- TGF-B superfamily receptor type I
- activin A receptor, type II-like kinase 2
- activin receptor type I
- activin receptor type-1
- activin receptor-like kinase 2
- hydroxyalkyl-protein kinase
- serine/threonine-protein kinase receptor R1
- ACTR-I
- SKR1
- TSR-I
- activin A receptor, type 1
- activin type I receptor
- type I TGF B receptor
- activin A receptor, type I
- activin receptor type IA
- TSK-7L
- activin A receptor type 1 S homeolog
- activin A receptor type I S homeolog
- activin receptor like kinase-2
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