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ACVR2A Produkte

(Activin A Receptor, Type IIA (ACVR2A))
This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. [provided by RefSeq, Jul 2008].

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Ausgewählte ACVR2A Kategorien

ACVR2A Antikörper

High quality antibodies with extensive validation data.

ACVR2A ELISA Kits

Reliable ELISA kits for a wide range of species.

ACVR2A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ACVR2A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (9)
Kat. Nr. ABIN7438676
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (6)
Kat. Nr. ABIN3015792
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7427552
Menge 100 μL
Datenblatt Datenblatt

Empfohlene ACVR2A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6953429
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6964578
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4881727
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ACVR2A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Baculovirus infected Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN5854601
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1305813
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1305811
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ACVR2A Produkten

Portale, Cricrì, Bresolin, Lupi, Gaspari, Silvestri, Russo, Marino, Ubezio, Pagni, Vergani, Kronnie, Valsecchi, Locatelli, Rizzari, Biondi, Dander, DAmico: "ActivinA: a new leukemia-promoting factor conferring migratory advantage to B-cell precursor-acute lymphoblastic leukemic cells." in: Haematologica, Vol. 104, Issue 3, pp. 533-545, (2019) (PubMed).

Lodberg, van der Eerden, Boers-Sijmons, Thomsen, Brüel, van Leeuwen, Eijken: "A follistatin-based molecule increases muscle and bone mass without affecting the red blood cell count in mice." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 5, pp. 6001-6010, (2019) (PubMed).

Reichel, Farmer, Gmeiner, Walpurgis, Thevis: "Detection of Sotatercept (ACE-011) in human serum by SAR-PAGE and western single blotting." in: Drug testing and analysis, Vol. 10, Issue 6, pp. 927-937, (2018) (PubMed).

Iwata, Hacia, Suzuki, Sanchez-Lara, Urata, Chai: "Modulation of noncanonical TGF-? signaling prevents cleft palate in Tgfbr2 mutant mice." in: The Journal of clinical investigation, Vol. 122, Issue 3, pp. 873-85, (2012) (PubMed).

Martins da Silva, Bayne, Cambray, Hartley, McNeilly, Anderson: "Expression of activin subunits and receptors in the developing human ovary: activin A promotes germ cell survival and proliferation before primordial follicle formation." in: Developmental biology, Vol. 266, Issue 2, pp. 334-45, (2004) (PubMed).

Jung, Doctolero, Tajima, Nguyen, Keku, Sandler, Carethers: "Loss of activin receptor type 2 protein expression in microsatellite unstable colon cancers." in: Gastroenterology, Vol. 126, Issue 3, pp. 654-9, (2004) (PubMed).

Olaru, Mori, Yin, Wang, Kimos, Perry, Xu, Sato, Selaru, Deacu, Sterian, Shibata, Abraham, Meltzer: "Loss of heterozygosity and mutational analyses of the ACTRII gene locus in human colorectal tumors." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 83, Issue 12, pp. 1867-71, (2003) (PubMed).

Synonyme und alternative Namen zu ACVR2A

activin A receptor type 2A (ACVR2A), activin A receptor type 2A (acvr2a), activin A receptor type 2A (Acvr2a), activin A receptor type 2A L homeolog (acvr2a.L), activin A receptor type 2Aa (acvr2aa), activin receptor IIA (Acvr2a), actr2a, actrii, ACTRII, ActrIIa, ACVR2, acvr2, Acvr2, ACVR2A, acvr2a, rActR-II, TactrII, wu:fa02e10, XSTK9

Bezeichner auf Proteinebene für ACVR2A

  • activin receptor IIA
  • activin receptor type-2A
  • activin A receptor, type IIA
  • ACTR-IIA
  • activin receptor type IIA
  • type II activin receptor
  • activin A receptor, type II
  • activin receptor, type IIA
  • ACTRIIA
  • activin receptor type II
  • activin type 2 receptor
  • activin receptor IIa
  • etID22865.9
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