Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

ACVR2B Produkte

(Activin A Receptor, Type IIB (ACVR2B))

Kategorien

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq, Jul 2008].

antibodies-online.com steht für hochwertige Forschungsprodukte. Suchen, finden und bestellen Sie Tools mit umfangreichen Validierungsdaten, Bildern, Referenzen. Unser wissenschaftlicher Kundenservice steht Ihnen jederzeit zur Verfügung, wenn Sie Fragen zur Auswahl oder Anwendung unserer Produkte haben.

Ausgewählte ACVR2B Kategorien

ACVR2B Antikörper

High quality antibodies with extensive validation data.

ACVR2B ELISA Kits

Reliable ELISA kits for a wide range of species.

ACVR2B Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ACVR2B Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat, Sheep, Zebrafish (Danio rerio)
Applikation WB
Validierungen
  • (5)
Kat. Nr. ABIN2782110
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Rat
Applikation WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validierungen
  • (3)
Kat. Nr. ABIN1714650
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
  • (2)
Kat. Nr. ABIN391162
Menge 400 μL
Datenblatt Datenblatt

Empfohlene ACVR2B ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953430
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4881730
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6385086
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ACVR2B Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1305815
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1305817
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN7320385
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ACVR2B Produkten

Iwata, Hacia, Suzuki, Sanchez-Lara, Urata, Chai: "Modulation of noncanonical TGF-? signaling prevents cleft palate in Tgfbr2 mutant mice." in: The Journal of clinical investigation, Vol. 122, Issue 3, pp. 873-85, (2012) (PubMed).

McKay, Ogborn, Bellamy, Tarnopolsky, Parise: "Myostatin is associated with age-related human muscle stem cell dysfunction." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 26, Issue 6, pp. 2509-21, (2012) (PubMed).

Martins da Silva, Bayne, Cambray, Hartley, McNeilly, Anderson: "Expression of activin subunits and receptors in the developing human ovary: activin A promotes germ cell survival and proliferation before primordial follicle formation." in: Developmental biology, Vol. 266, Issue 2, pp. 334-45, (2004) (PubMed).

Harrison, Gray, Fischer, Donaldson, Choe, Vale: "An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28036-44, (2004) (PubMed).

Casagrandi, Bearfield, Geary, Redman, Muttukrishna: "Inhibin, activin, follistatin, activin receptors and beta-glycan gene expression in the placental tissue of patients with pre-eclampsia." in: Molecular human reproduction, Vol. 9, Issue 4, pp. 199-203, (2003) (PubMed).

Synonyme und alternative Namen zu ACVR2B

activin A receptor type 2B (ACVR2B), activin A receptor type 2B (acvr2b), activin A receptor type 2B L homeolog (acvr2b.L), activin A receptor type 2B (Acvr2b), activin A receptor type 2Ba (acvr2ba), activin receptor IIB (Acvr2b), actr-iib, ActR-IIB, actr2b, actriib, ACTRIIB, ActRIIB, actrIIb, ACVR2B, HTX4, wu:fj97d11, XAR1

Bezeichner auf Proteinebene für ACVR2B

  • activin A receptor, type IIB
  • activin receptor type IIB
  • activin receptor type-2B-like
  • activin type IIB receptor
  • activin receptor type-2B
  • ACTR-IIB
  • testicular activin receptor IIB
  • ActRIIB type II activin receptor B
  • Activine receptor 2b (transmembrane serine kinase)
  • activin receptor IIB
Sie sind hier:
Kundenservice