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ACVRL1 Produkte

(Activin A Receptor Type II-Like 1 (ACVRL1))
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008].

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Ausgewählte ACVRL1 Kategorien

ACVRL1 Antikörper

High quality antibodies with extensive validation data.

ACVRL1 ELISA Kits

Reliable ELISA kits for a wide range of species.

ACVRL1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ACVRL1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, FACS, IHC (p)
Validierungen
  • (4)
  • (5)
Kat. Nr. ABIN392241
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IHC, FACS
Validierungen
  • (7)
Kat. Nr. ABIN3029853
Menge 0.4 mL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7183058
Menge 100 μL
Datenblatt Datenblatt

Empfohlene ACVRL1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953428
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN5510685
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN5510686
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ACVRL1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7273821
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Human Cells
Validierungen
  • (1)
Kat. Nr. ABIN7320736
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1305819
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ACVRL1 Produkten

Chen, Qin, Li, Wang, Dahlman, Malagon-Lopez, Gujja, Cilfone, Kauffman, Sun, Sun, Zhang, Aryal, Canfran-Duque, Liu, Kusters, Sehgal, Jiao, Anderson, Gulcher, Fernandez-Hernando, Lutgens, Schwartz et al.: "Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis. ..." in: Nature metabolism, Vol. 1, Issue 9, pp. 912-926, (2019) (PubMed).

Muñoz-Félix, Cuesta, Perretta-Tejedor, Subileau, López-Hernández, López-Novoa, Martínez-Salgado: "Identification of bone morphogenetic protein 9 (BMP9) as a novel profibrotic factor in vitro." in: Cellular signalling, Vol. 28, Issue 9, pp. 1252-61, (2017) (PubMed).

Sanz-Ramos, Dotor, Izal-Azcárate: "The role of Alk-1 and Alk-5 in the mechanosensing of chondrocytes." in: Cellular & molecular biology letters, Vol. 19, Issue 4, pp. 659-74, (2014) (PubMed).

Antonov, Antonova, Fujii, ten Dijke, Handa, Catravas, Verin: "Regulation of endothelial barrier function by TGF-? type I receptor ALK5: potential role of contractile mechanisms and heat shock protein 90." in: Journal of cellular physiology, Vol. 227, Issue 2, pp. 759-71, (2011) (PubMed).

Cunha, Pardali, Thorikay, Anderberg, Hawinkels, Goumans, Seehra, Heldin, ten Dijke, Pietras: "Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis." in: The Journal of experimental medicine, Vol. 207, Issue 1, pp. 85-100, (2010) (PubMed).

Finnson, Parker, ten Dijke, Thorikay, Philip: "ALK1 opposes ALK5/Smad3 signaling and expression of extracellular matrix components in human chondrocytes." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 23, Issue 6, pp. 896-906, (2008) (PubMed).

Yu, Pisitkun, Wang, Shen, Knepper: "LC-MS/MS analysis of apical and basolateral plasma membranes of rat renal collecting duct cells." in: Molecular & cellular proteomics : MCP, Vol. 5, Issue 11, pp. 2131-45, (2006) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Berg, Gallione, Stenzel, Johnson, Allen, Schwartz, Jackson, Porteous, Marchuk: "The activin receptor-like kinase 1 gene: genomic structure and mutations in hereditary hemorrhagic telangiectasia type 2." in: American journal of human genetics, Vol. 61, Issue 1, pp. 60-7, (1997) (PubMed).

Johnson, Berg, Baldwin, Gallione, Marondel, Yoon, Stenzel, Speer, Pericak-Vance, Diamond, Guttmacher, Jackson, Attisano, Kucherlapati, Porteous, Marchuk: "Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2." in: Nature genetics, Vol. 13, Issue 2, pp. 189-95, (1996) (PubMed).

Synonyme und alternative Namen zu ACVRL1

activin A receptor like type 1 (ACVRL1), activin A receptor type II-like 1 (ACVRL1), activin A receptor like type 1 (acvrl1), activin A receptor like type 1 (Acvrl1), activin A receptor, type II-like 1 (Acvrl1), ACVRL1, ACVRLK1, Acvrlk1, AI115505, AI427544, ALK-1, alk1, ALK1, Alk1, HHT, HHT2, hm:zehn1109, ORW2, R-3, R3, SETHKIR, SKR3, TSR-I, vgb, zehn1109

Bezeichner auf Proteinebene für ACVRL1

  • activin A receptor type II-like 1
  • serine/threonine-protein kinase receptor R3
  • serine/threonine-protein kinase receptor R3-like
  • activin receptor-like kinase 1
  • vbg
  • violet beauregarde
  • TGF-B superfamily receptor type I
  • activin A receptor, type II-like kinase 1
  • Activin receptor like kinase 1
  • SKR3
  • TSR-I
  • ALK-1
  • activin receptor-like kinase-1
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