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ADAM17 Produkte

(ADAM Metallopeptidase Domain 17 (ADAM17))
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme\; binds mitotic arrest deficient 2 protein\; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq, Jul 2008].

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Ausgewählte ADAM17 Kategorien

ADAM17 Antikörper

High quality antibodies with extensive validation data.

ADAM17 ELISA Kits

Reliable ELISA kits for a wide range of species.

ADAM17 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ADAM17 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, ICC, IP
Validierungen
  • (8)
Kat. Nr. ABIN7426310
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p), PLA
Validierungen
  • (1)
  • (5)
Kat. Nr. ABIN563080
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN705671
Menge 100 μL
Datenblatt Datenblatt

Empfohlene ADAM17 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (5)
Kat. Nr. ABIN6730919
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6974750
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953448
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ADAM17 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7121690
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1305853
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Mammalian Cells
Validierungen
  • (1)
Kat. Nr. ABIN7538118
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ADAM17 Produkten

Six, Debaene, Van den Hauwe, De Rycke, Gardiner, Compernolle, Feys: "GPIbα shedding in platelets is controlled by strict intracellular containment of both enzyme and substrate." in: Journal of thrombosis and haemostasis : JTH, (2023) (PubMed).

Beke Debreceni, Szász, Kónya, Erdődi, Kiss, Kappelmayer: "L-Selectin Expression is Influenced by Phosphatase Activity in Chronic Lymphocytic Leukemia." in: Cytometry. Part B, Clinical cytometry, Vol. 96, Issue 2, pp. 149-157, (2020) (PubMed).

Yousef, Saleh, Abd-Allah, Elnagar, Akool: "PEG-SOD attenuates the mitogenic ERK1/2 signaling cascade induced by cyclosporin A in the liver and kidney of albino mice." in: Chemico-biological interactions, Vol. 330, pp. 109245, (2020) (PubMed).

Dreschers, Platen, Ludwig, Gille, Köstlin, Orlikowsky: "Metalloproteinases TACE and MMP-9 Differentially Regulate Death Factors on Adult and Neonatal Monocytes After Infection with Escherichia coli." in: International journal of molecular sciences, Vol. 20, Issue 6, (2019) (PubMed).

Hirayama, Awano, Seta, Ansai: "ADAM17 regulates TNF-α expression upon lipopolysaccharide stimulation in oral keratinocytes." in: Biomedical research (Tokyo, Japan), Vol. 38, Issue 3, pp. 157-165, (2018) (PubMed).

Lécuyer, Virion, Barnier, Matczak, Bourdoulous, Bianchini, Saller, Borgel, Nassif, Coureuil: "An ADAM-10 dependent EPCR shedding links meningococcal interaction with endothelial cells to purpura fulminans." in: PLoS pathogens, Vol. 14, Issue 4, pp. e1006981, (2018) (PubMed).

Wang, Wang, Yin, Zhang, Yu, Kong, Yuan, Fang, Liu, Liu, Shi: "Reduced neurotrophic factor level is the early event before the functional neuronal deficiency in high-fat diet induced obese mice." in: Metabolic brain disease, Vol. 32, Issue 1, pp. 247-257, (2018) (PubMed).

Sun, Jiang, Lu, Chen, Tao, Chen: "Therapeutic potential of ADAM17 modulation in gastric cancer through regulation of the EGFR and TNF-α signalling pathways." in: Molecular and cellular biochemistry, Vol. 426, Issue 1-2, pp. 17-26, (2017) (PubMed).

Serra, Gallelli, Butrico, Buffone, Caliò, De Caridi, Massara, Barbetta, Amato, Labonia, Mimmi, Iaccino, de Franciscis: "From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases." in: International wound journal, (2016) (PubMed).

Sharma, Bender, Zimmermann, Riesterer, Broggini-Tenzer, Pruschy: "Secretome Signature Identifies ADAM17 as Novel Target for Radiosensitization of Non-Small Cell Lung Cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 17, pp. 4428-39, (2016) (PubMed).

Synonyme und alternative Namen zu ADAM17

ADAM metallopeptidase domain 17 (ADAM17), a disintegrin and metallopeptidase domain 17 (Adam17), ADAM metallopeptidase domain 17b (adam17b), ADAM metallopeptidase domain 17 L homeolog (adam17.L), ADAM metallopeptidase domain 17 (Adam17), ADAM metallopeptidase domain 17a (adam17a), adam17, ADAM18, adam18, CD156B, CD156b, cd156b, CSVP, csvp, fc20b01, NISBD, si:dkey-81b15.2, TACE, Tace, tace, wu:fc20b01, zgc:63886

Bezeichner auf Proteinebene für ADAM17

  • ADAM metallopeptidase domain 18
  • TNF-alpha convertase
  • TNF-alpha converting enzyme
  • disintegrin and metalloproteinase domain-containing protein 17
  • snake venom-like protease
  • tumor necrosis factor, alpha, converting enzyme
  • ADAM 17
  • TNF-alpha-converting enzyme
  • a disintegrin and metalloprotease domain 17; TNF-alpha converting enzyme
  • a disintegrin and metalloproteinase domain 17
  • a disintegrin and metallopeptidase domain 17
  • ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme)
  • a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme)
  • tumor necrosis factor alpha converting enzyme
  • ADAM metallopeptidase domain 17
  • a disintegrin and metalloprotease domain 17
  • disintegrin metalloproteinase
  • disintegrin and metalloproteinase domain-containing protein 17-like
  • ADAM metallopeptidase domain 17a
  • DKEY-174C12.1
  • a disintegrin and metalloproteinase domain 17a
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