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ADAMTS13 Produkte

(ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13))
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2008].

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Ausgewählte ADAMTS13 Kategorien

ADAMTS13 Antikörper

High quality antibodies with extensive validation data.

ADAMTS13 ELISA Kits

Reliable ELISA kits for a wide range of species.

ADAMTS13 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ADAMTS13 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (4)
Kat. Nr. ABIN7265440
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (2)
Kat. Nr. ABIN7432937
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (2)
Kat. Nr. ABIN564816
Menge 50 μL
Datenblatt Datenblatt

Empfohlene ADAMTS13 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6953460
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6964600
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6964599
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ADAMTS13 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1305888
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7505139
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7392824
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ADAMTS13 Produkten

Tati, Kristoffersson, Manea Hedström, Mörgelin, Wieslander, van Kooten, Karpman: "Neutrophil Protease Cleavage of Von Willebrand Factor in Glomeruli - An Anti-thrombotic Mechanism in the Kidney." in: EBioMedicine, Vol. 16, pp. 302-311, (2017) (PubMed).

Liu, Guo, Zhang, Liu, Wen, Yang, Yang, Liu: "The Expression of Tristetraprolin and Its Relationship with Urinary Proteins in Patients with Diabetic Nephropathy." in: PLoS ONE, Vol. 10, Issue 10, pp. e0141471, (2016) (PubMed).

Feng, Eyler, Zhang, Maga, Nester, Kroll, Smith, Afshar-Kharghan: "Partial ADAMTS13 deficiency in atypical hemolytic uremic syndrome." in: Blood, Vol. 122, Issue 8, pp. 1487-93, (2013) (PubMed).

Feng, Liang, Cruz, Vu, Zhou, Pemmaraju, Dong, Kroll, Afshar-Kharghan: "The interaction between factor H and Von Willebrand factor." in: PLoS ONE, Vol. 8, Issue 8, pp. e73715, (2013) (PubMed).

Hershko, Simhadri, Blaisdell, Hunt, Newell, Tseng, Hershko, Choi, Sauna, Wu, Bram, Komar, Kimchi-Sarfaty: "Cyclosporin A impairs the secretion and activity of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeat)." in: The Journal of biological chemistry, Vol. 287, Issue 53, pp. 44361-71, (2012) (PubMed).

Hunt, Geetha, Allen, Hershko, Fathke, Kong, Plum, Struble, Soejima, Friedman, Garfield, Balaji, Kimchi-Sarfaty: "Detection of a secreted metalloprotease within the nuclei of liver cells." in: Molecular bioSystems, Vol. 7, Issue 6, pp. 2012-8, (2011) (PubMed).

Ganburged, Suda, Saito, Yamazaki, Isokawa, Moriyama: "Dilated capillaries, disorganized collagen fibers and differential gene expression in periodontal ligaments of hypomorphic fibrillin-1 mice." in: Cell and tissue research, Vol. 341, Issue 3, pp. 381-95, (2010) (PubMed).

Turner, Nolasco, Ruggeri, Moake: "Endothelial cell ADAMTS-13 and VWF: production, release, and VWF string cleavage." in: Blood, Vol. 114, Issue 24, pp. 5102-11, (2009) (PubMed).

Sen, Tyagi, Patibandla, Dean, Tyagi, Roberts, Lominadze: "Fibrinogen-induced endothelin-1 production from endothelial cells." in: American journal of physiology. Cell physiology, Vol. 296, Issue 4, pp. C840-7, (2009) (PubMed).

Chung, Popova, Jorgensen, Dong, Chandhoke, Bailey, Popov: "Degradation of circulating von Willebrand factor and its regulator ADAMTS13 implicates secreted Bacillus anthracis metalloproteases in anthrax consumptive coagulopathy." in: The Journal of biological chemistry, Vol. 283, Issue 15, pp. 9531-42, (2008) (PubMed).

Synonyme und alternative Namen zu ADAMTS13

ADAM metallopeptidase with thrombospondin type 1 motif 13 (ADAMTS13), a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 (Adamts13), ADAM metallopeptidase with thrombospondin type 1 motif, 13 (adamts13), ADAM metallopeptidase with thrombospondin type 1 motif, 13 (Adamts13), ADAM metallopeptidase with thrombospondin type 1 motif 13 (Adamts13), ADAM-TS13, ADAMTS-13, ADAMTS13, C9orf8, Gm710, vWF-CP, VWFCP

Bezeichner auf Proteinebene für ADAMTS13

  • ADAM metallopeptidase with thrombospondin type 1 motif, 13
  • A disintegrin and metalloproteinase with thrombospondin motifs 13
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13
  • vWF-cleaving protease
  • von Willebrand factor-cleaving protease
  • ADAM-TS 13
  • ADAM-TS13
  • ADAMTS-13
  • ADAMTS13 isoform IAP-b
  • vWF-CP mRNA for von Willebrand factor-cleaving
  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 isoform 1 preproprotein-like
  • A disintegrin and metalloproteinase with thrombospondin motifs 13-like
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13
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