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ADAMTS5 Produkte

(ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5))
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage. [provided by RefSeq, Jul 2008].

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Ausgewählte ADAMTS5 Kategorien

ADAMTS5 Antikörper

High quality antibodies with extensive validation data.

ADAMTS5 ELISA Kits

Reliable ELISA kits for a wide range of species.

ADAMTS5 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ADAMTS5 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN3016806
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (4)
Kat. Nr. ABIN7436774
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN2854716
Menge 100 μL
Datenblatt Datenblatt

Empfohlene ADAMTS5 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (7)
  • (1)
Kat. Nr. ABIN6953465
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953466
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rabbit
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953468
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ADAMTS5 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1305905
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7399937
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Rat
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7409563
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ADAMTS5 Produkten

Wang, Ye, Ye, Wang, Liu, Jiang, Xu, Zhang, Chen, Wan: "ADAMTS-5 Decreases in Coronary Arteries and Plasma from Patients with Coronary Artery Disease." in: Disease markers, Vol. 2019, pp. 6129748, (2020) (PubMed).

Yilmaz, Melekoglu, Taskapan, Olmez Budak, Toprak: "The investigation of serum levels of ADAMTS 5 and 8 (the A disintegrin and metalloproteinase with thrombospondin motifs) in the etiology of endometrial cancer." in: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, Vol. 40, Issue 6, pp. 856-859, (2020) (PubMed).

Si, Yang, Li, Tian, Zhou, Li, Huang, Kang, Yang, Zhou, Cheng, Shen: "miR-140 Attenuates the Progression of Early-Stage Osteoarthritis by Retarding Chondrocyte Senescence." in: Molecular therapy. Nucleic acids, Vol. 19, pp. 15-30, (2019) (PubMed).

Tajima, Sekimoto, Yamaguchi, Taniguchi, Kurogi, Maruyama, Chosa: "Hemoglobin stimulates the expression of ADAMTS-5 and ADAMTS-9 by synovial cells: a possible cause of articular cartilage damage after intra-articular hemorrhage." in: BMC musculoskeletal disorders, Vol. 18, Issue 1, pp. 449, (2018) (PubMed).

Huang, Song, Li, Xiao, Chen, Gong, Zeng, Yang, Chen: "Pellet coculture of osteoarthritic chondrocytes and infrapatellar fat pad-derived mesenchymal stem cells with chitosan/hyaluronic acid nanoparticles promotes chondrogenic differentiation." in: Stem cell research & therapy, Vol. 8, Issue 1, pp. 264, (2018) (PubMed).

Mao, Wu, Zhang, Zhang, Liao, Li, Kang: "MicroRNA-92a-3p Regulates Aggrecanase-1 and Aggrecanase-2 Expression in Chondrogenesis and IL-1β-Induced Catabolism in Human Articular Chondrocytes." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 44, Issue 1, pp. 38-52, (2018) (PubMed).

Si, Zeng, Liu, Zhou, Chen, Cheng, Lu, Shen: "Intra-articular injection of microRNA-140 (miRNA-140) alleviates osteoarthritis (OA) progression by modulating extracellular matrix (ECM) homeostasis in rats." in: Osteoarthritis and cartilage, Vol. 25, Issue 10, pp. 1698-1707, (2018) (PubMed).

Mern, Tschugg, Hartmann, Thomé et al.: "Self-complementary adeno-associated virus serotype 6 mediated knockdown of ADAMTS4 induces long-term and effective enhancement of aggrecan in degenerative human nucleus pulposus cells: A new ..." in: PLoS ONE, Vol. 12, Issue 2, pp. e0172181, (2017) (PubMed).

Pérez-García, Carrión, Gutiérrez-Cañas, González-Álvaro, Gomariz, Juarranz: "VIP and CRF reduce ADAMTS expression and function in osteoarthritis synovial fibroblasts." in: Journal of cellular and molecular medicine, Vol. 20, Issue 4, pp. 678-87, (2016) (PubMed).

Serra, Gallelli, Butrico, Buffone, Caliò, De Caridi, Massara, Barbetta, Amato, Labonia, Mimmi, Iaccino, de Franciscis: "From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases." in: International wound journal, (2016) (PubMed).

Synonyme und alternative Namen zu ADAMTS5

ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5), ADAM metallopeptidase with thrombospondin type 1 motif 5 (adamts5), a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) (Adamts5), ADAM metallopeptidase with thrombospondin type 1 motif, 5 (Adamts5), 9530092O11Rik, ADAM-TS5, ADAM-TS 5, ADAM-TS 11, ADAMTS-5, ADAMTS-11, ADAMTS1, ADAMTS11, ADMP-2, AI481094, ASMP-2

Bezeichner auf Proteinebene für ADAMTS5

  • ADAM metallopeptidase with thrombospondin type 1 motif, 5
  • a disintegrin and metalloproteinase with thrombospondin motifs 5-like
  • A disintegrin and metalloproteinase with thrombospondin motifs 5
  • ADAM-TS 5
  • ADAMTS-5
  • ADMP-2
  • aggrecanase-2
  • implantin
  • a disintegrin and metalloproteinase with thrombospondin motifs 11
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
  • ADAM-TS5
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
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