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ADD3 Produkte

(Adducin 3 (Gamma) (ADD3))

Kategorien

Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced adducin gamma transcripts encoding different isoforms have been described. The functions of the different isoforms are not known. [provided by RefSeq, Jul 2008].

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Ausgewählte ADD3 Kategorien

ADD3 Antikörper

High quality antibodies with extensive validation data.

ADD3 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ADD3 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (5)
Kat. Nr. ABIN559788
Menge 50 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IF, IHC, ICC
Validierungen
  • (4)
Kat. Nr. ABIN6257585
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, IHC
Validierungen
  • (2)
Kat. Nr. ABIN7185801
Menge 100 μg
Datenblatt Datenblatt

Empfohlene ADD3 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6208555
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ADD3 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1305971
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7421470
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2721672
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ADD3 Produkten

Fallon, Moreau, Croft, Labib, Gu, Fon: "Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain." in: The Journal of biological chemistry, Vol. 277, Issue 1, pp. 486-91, (2002) (PubMed).

Bowery, Brown: "The cloning of GABA(B) receptors." in: Nature, Vol. 386, Issue 6622, pp. 223-4, (1997) (PubMed).

Dong, OBrien, Fung, Lanahan, Worley, Huganir: "GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors." in: Nature, Vol. 386, Issue 6622, pp. 279-84, (1997) (PubMed).

Synonyme und alternative Namen zu ADD3

adducin 3 (gamma) (ADD3), adducin 3 (add3), adducin 3 (ADD3), adducin 3 L homeolog (add3.L), adducin 3 (gamma) (Add3), adducin 3 (Add3), add3, ADD3, ADDL, AI463285, DKFZp459E0630, gamma-adducin, MGC89418, R75380

Bezeichner auf Proteinebene für ADD3

  • gamma-adducin
  • adducin 3 (gamma)
  • adducin 3 gamma
  • gamma-adducin-like
  • adducin-like protein 70
  • cytoskeletal protein
  • potein kinase C binding protein 35H
  • protein kinase C-binding protein 35H
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