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AICDA Produkte

(Activation-Induced Cytidine Deaminase (AICDA))

Kategorien

This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009].

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Ausgewählte AICDA Kategorien

AICDA Antikörper

High quality antibodies with extensive validation data.

AICDA ELISA Kits

Reliable ELISA kits for a wide range of species.

AICDA Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene AICDA Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF, ICC, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN2855890
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IF, EIA
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN499233
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN3181420
Menge 100 μL
Datenblatt Datenblatt

Empfohlene AICDA ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953423
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Dog
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN5593414
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6212552
Menge 96 tests
Datenblatt Datenblatt

Empfohlene AICDA Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN1098741
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1344654
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN2127824
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren AICDA Produkten

Milillo, Molinario, Costanzi, Vischini, La Carpia, La Greca, Rigante, Gambaro, Gurrieri, Sangiorgi: "Defective activation of the MAPK/ERK pathway, leading to PARP1 and DNMT1 dysregulation, is a common defect in IgA nephropathy and Henoch-Schönlein purpura." in: Journal of nephrology, Vol. 31, Issue 5, pp. 731-741, (2018) (PubMed).

Demberg, Mohanram, Musich, Brocca-Cofano, McKinnon, Venzon, Robert-Guroff: "Loss of marginal zone B-cells in SHIVSF162P4 challenged rhesus macaques despite control of viremia to low or undetectable levels in chronic infection." in: Virology, Vol. 484, pp. 323-333, (2015) (PubMed).

Cortizas, Zahn, Hajjar, Patenaude, Di Noia, Verdun: "Alternative end-joining and classical nonhomologous end-joining pathways repair different types of double-strand breaks during class-switch recombination." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 11, pp. 5751-63, (2013) (PubMed).

Ito, Murakami, Suzuki, Mochida, Suzuki, Ikebuchi, Yamaguchi, Mizuochi: "Enhanced expression of lymphomagenesis-related genes in peripheral blood B cells of chronic hepatitis C patients." in: Clinical immunology (Orlando, Fla.), Vol. 135, Issue 3, pp. 459-65, (2010) (PubMed).

Kotani, Kakazu, Tsuruyama, Okazaki, Muramatsu, Kinoshita, Nagaoka, Yabe, Honjo: "Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 5, pp. 1616-20, (2007) (PubMed).

Crouch, Li, Takizawa, Fichtner-Feigl, Gourzi, Montaño, Feigenbaum, Wilson, Janz, Papavasiliou, Casellas: "Regulation of AID expression in the immune response." in: The Journal of experimental medicine, Vol. 204, Issue 5, pp. 1145-56, (2007) (PubMed).

Larijani, Petrov, Kolenchenko, Berru, Krylov, Martin: "AID associates with single-stranded DNA with high affinity and a long complex half-life in a sequence-independent manner." in: Molecular and cellular biology, Vol. 27, Issue 1, pp. 20-30, (2006) (PubMed).

Besmer, Market, Papavasiliou: "The transcription elongation complex directs activation-induced cytidine deaminase-mediated DNA deamination." in: Molecular and cellular biology, Vol. 26, Issue 11, pp. 4378-85, (2006) (PubMed).

Cascalho: "Advantages and disadvantages of cytidine deamination." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 11, pp. 6513-8, (2004) (PubMed).

Greeve, Philipsen, Krause, Klapper, Heidorn, Castle, Janda, Marcu, Parwaresch: "Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas." in: Blood, Vol. 101, Issue 9, pp. 3574-80, (2003) (PubMed).

Synonyme und alternative Namen zu AICDA

activation induced cytidine deaminase (AICDA), activation-induced cytidine deaminase (Aicda), activation-induced cytidine deaminase (aicda), activation-induced cytidine deaminase L homeolog (aicda.L), activation induced cytidine deaminase (aicda), AICDA, AID, Aid, aid, ARP2, Arp2, arp2, CDA2, cda2, HIGM2, higm2, xlaid

Bezeichner auf Proteinebene für AICDA

  • cytidine aminohydrolase
  • integrated into Burkitt's lymphoma cell line Ramos
  • single-stranded DNA cytosine deaminase
  • activation induced deaminase
  • activation-induced cytidine deaminase
  • aid
  • activation induced cytidine deaminase
  • activation-induced deaminase
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