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AKAP13 Produkte

(A Kinase (PRKA) Anchor Protein 13 (AKAP13))

Kategorien

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta. [provided by RefSeq, Jul 2012].

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Ausgewählte AKAP13 Kategorien

AKAP13 Antikörper

High quality antibodies with extensive validation data.

Empfohlene AKAP13 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (6)
Kat. Nr. ABIN524646
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN564877
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC, ELISA, IF, ICC
Validierungen
  • (3)
Kat. Nr. ABIN6256897
Menge 100 μL
Datenblatt Datenblatt

Empfohlene AKAP13 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN5648000
Menge 96 tests
Datenblatt Datenblatt

Empfohlene AKAP13 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7121629
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1344715
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren AKAP13 Produkten

Hu, Wang, Li, Yang, Zhang, Chen, Wang, Zhou: "The mRNA and protein expression of A-kinase anchor proteins 13 in human colorectal cancer." in: Clinical and experimental medicine, Vol. 10, Issue 1, pp. 41-9, (2010) (PubMed).

Manukyan, Nalbant, Luxen, Hahn, Knaus: "RhoA GTPase activation by TLR2 and TLR3 ligands: connecting via Src to NF-kappa B." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 6, pp. 3522-9, (2009) (PubMed).

Baisamy, Cavin, Jurisch, Diviani: "The ubiquitin-like protein LC3 regulates the Rho-GEF activity of AKAP-Lbc." in: The Journal of biological chemistry, Vol. 284, Issue 41, pp. 28232-42, (2009) (PubMed).

Synonyme und alternative Namen zu AKAP13

A-kinase anchoring protein 13 (AKAP13), A-kinase anchoring protein 13 S homeolog (akap13.S), A kinase (PRKA) anchor protein 13 (akap13), A-kinase anchoring protein 13 (Akap13), A kinase (PRKA) anchor protein 13 (Akap13), 1700026G02Rik, 5730522G15Rik, 5830460E08Rik, AKAP-13, akap-lbc, AKAP-Lbc, AKAP13, arhgef13, ARHGEF13, brx, BRX, c-lbc, ha-3, HA-3, ht31, Ht31, lbc, LBC, MGC81410, p47, PRKA13, proto-lb, PROTO-LB, proto-lbc, PROTO-LBC

Bezeichner auf Proteinebene für AKAP13

  • A kinase (PRKA) anchor protein 13
  • A kinase anchor protein 13 isoform-like
  • A-kinase anchor protein 13-like
  • A-kinase anchor protein 13
  • a-kinase anchor protein 13-like
  • A-kinase anchoring protein
  • LBC oncogene
  • breast cancer nuclear receptor-binding auxiliary protein
  • guanine nucleotide exchange factor Lbc
  • human thyroid-anchoring protein 31
  • lymphoid blast crisis oncogene
  • non-oncogenic Rho GTPase-specific GTP exchange factor
  • protein kinase A-anchoring protein 13
  • protein kinase A anchoring protein Rt31
  • type II cAMP-dependent protein kinase anchoring protein Ht31
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