AKR1C2 Produkte
(Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
Kategorien
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
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Ausgewählte AKR1C2 Kategorien
AKR1C2 Antikörper
High quality antibodies with extensive validation data.
AKR1C2 ELISA Kits
Reliable ELISA kits for a wide range of species.
AKR1C2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene AKR1C2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (7)
Kat. Nr.
ABIN7265549
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, StM
Validierungen
- (5)
Kat. Nr.
ABIN6939232
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN560582
Menge
50 μL
Datenblatt
Datenblatt
Empfohlene AKR1C2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6953599
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5653669
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene AKR1C2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7121783
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1344758
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1344756
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren AKR1C2 Produkten
: "Aldo-keto reductase and sorbitol dehydrogenase enzymes in Egyptian diabetic patients with and without proliferative diabetic retinopathy." in: Clinical & experimental optometry, Vol. 96, Issue 3, pp. 303-9, (2013) (PubMed).: "Proteomics-based identification of secreted protein dihydrodiol dehydrogenase 2 as a potential biomarker for predicting cisplatin efficacy in advanced NSCLC patients." in: Lung cancer (Amsterdam, Netherlands), Vol. 77, Issue 2, pp. 427-32, (2012) (PubMed).
: "Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 239-49, (2011) (PubMed).
: "Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 217-26, (2011) (PubMed).
: "Aldo-keto reductase 1C2 fails to metabolize doxorubicin and daunorubicin in vitro." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 36, Issue 6, pp. 991-4, (2008) (PubMed).
: "Aldo-keto reductase 1C2 is essential for 1-nitropyrene's but not for benzo[a]pyrene's induction of p53 phosphorylation and apoptosis." in: Toxicology, Vol. 244, Issue 2-3, pp. 257-70, (2008) (PubMed).
Synonyme und alternative Namen zu AKR1C2
aldo-keto reductase family 1 member C2 (AKR1C2), aldo-keto reductase family 1, member C2 (Akr1c2), AKR1C-pseudo, Akr1c21, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8Bezeichner auf Proteinebene für AKR1C2
- 3-alpha-HSD3
- DD-2
- DD/BABP
- aldo-keto reductase family 1 member C2
- chlordecone reductase homolog HAKRD
- dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III
- pseudo-chlordecone reductase
- trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
- type II dihydrodiol dehydrogenase
- 17-alpha-HSD
- 17-alpha-hydroxysteroid dehydrogenase
- 3(or 17)-alpha-hydroxysteroid dehydrogenase
- 3-alpha-hydroxysteroid dehydrogenase
- aldo-keto reductase family 1 member C21
- aldo-keto reductase family 1, member C21
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