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ALAS1 Produkte

(Aminolevulinate, delta-, Synthase 1 (ALAS1))
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme\; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011].

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Ausgewählte ALAS1 Kategorien

ALAS1 Antikörper

High quality antibodies with extensive validation data.

ALAS1 ELISA Kits

Reliable ELISA kits for a wide range of species.

ALAS1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ALAS1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN559839
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC
Validierungen
  • (2)
Kat. Nr. ABIN7142600
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IF (cc)
Validierungen
  • (2)
Kat. Nr. ABIN5557346
Menge 100 μL
Datenblatt Datenblatt

Empfohlene ALAS1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953665
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN1742702
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Sheep
Analytical Method
Validierungen
Kat. Nr. ABIN1773606
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ALAS1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1344797
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Rat
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7398293
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN5505552
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ALAS1 Produkten

Lazareth, Poli, Bignon, Mirmiran, Rabant, Cohen, Schmitt, Puy, Karras, Gouya, Pallet: "Renal Function Decline With Small Interfering RNA Silencing Aminolevulinic Acid Synthase 1 (ALAS1)." in: Kidney international reports, Vol. 6, Issue 7, pp. 1904-1911, (2021) (PubMed).

Ju, Mizutani, Imamichi, Yazawa, Matsumura, Kawabe, Kanno, Umezawa, Kangawa, Miyamoto: "Nuclear receptor 5A (NR5A) family regulates 5-aminolevulinic acid synthase 1 (ALAS1) gene expression in steroidogenic cells." in: Endocrinology, Vol. 153, Issue 11, pp. 5522-34, (2012) (PubMed).

Seo, Park, Jeon, Park, Park, Lee, Chang, Chun: "Gonadotropin regulation of genes differentially expressed in response to PKCzeta inhibitor during ovulation in the rat." in: Life sciences, Vol. 85, Issue 3-4, pp. 153-60, (2009) (PubMed).

Leick, Wojtaszewski, Johansen, Kiilerich, Comes, Hellsten, Hidalgo, Pilegaard: "PGC-1alpha is not mandatory for exercise- and training-induced adaptive gene responses in mouse skeletal muscle." in: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 2, pp. E463-74, (2008) (PubMed).

Zheng, Shan, Lambrecht, Donohue, Bonkovsky: "Differential regulation of human ALAS1 mRNA and protein levels by heme and cobalt protoporphyrin." in: Molecular and cellular biochemistry, Vol. 319, Issue 1-2, pp. 153-61, (2008) (PubMed).

Synonyme und alternative Namen zu ALAS1

5'-aminolevulinate synthase 1 (ALAS1), aminolevulinic acid synthase 1 (Alas1), 5'-aminolevulinate synthase 1 (Alas1), 5'-aminolevulinate synthase 1 (alas1), 5'-aminolevulinate synthase 1 (alas1.S), alanyl-tRNA synthetase protein (alaS1), aminolevulinate, delta-, synthase 1 (alas1), ALAS, Alas-1, Alas-h, ALAS-H, ALAS-N, ALAS1, ALAS3, ALASH, ALASN, MIG4, wu:fb58d01, wu:fi12g09

Bezeichner auf Proteinebene für ALAS1

  • 5-aminolevulinate synthase, nonspecific, mitochondrial
  • 5-aminolevulinic acid synthase 1
  • ALAS-H
  • delta-ALA synthase 1
  • delta-aminolevulinate synthase 1
  • migration-inducing protein 4
  • aminolevulinate synthase H
  • succinyl-CoA: glycine C-succinyl transferase
  • 5-aminolevulinate synthase 1
  • ALA-S
  • ALAS-N
  • aminolevulinic acid synthase 1
  • delta-ALA synthetase
  • aminolevulinate, delta, synthase 1
  • delta-ALA synthetase 1
  • ALA-synthase
  • aminolevulinate, delta-, synthase 1
  • Delta-ALA synthetase
  • 5-aminolevulinate synthase, nonspecific, mitochondrial-like
  • 5-aminolevulinic acid synthase
  • alanyl-tRNA synthetase protein
  • aminolevulinate synthase 1
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