ALDH2 Produkte
(Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))
Kategorien
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Mar 2011].
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Ausgewählte ALDH2 Kategorien
ALDH2 Antikörper
High quality antibodies with extensive validation data.
ALDH2 ELISA Kits
Reliable ELISA kits for a wide range of species.
ALDH2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ALDH2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA, FACS, ICC
Validierungen
- (2)
- (8)
Kat. Nr.
ABIN1724795
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (2)
- (9)
Kat. Nr.
ABIN3021779
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IF, IHC (p), ICC
Validierungen
- (7)
Kat. Nr.
ABIN2855041
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene ALDH2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6953593
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6953594
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6964702
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ALDH2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN666745
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1344826
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1344828
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ALDH2 Produkten
: "Protein Phosphatase 2A Improves Cardiac Functional Response to Ischemia and Sepsis." in: International journal of molecular sciences, Vol. 23, Issue 9, (2022) (PubMed).: "Imaging PARP with [18F]rucaparib in pancreatic cancer models." in: European journal of nuclear medicine and molecular imaging, Vol. 49, Issue 11, pp. 3668-3678, (2022) (PubMed).
: "Fenofibrate -a PPARα agonist- increases alcohol dehydrogenase levels in the liver: implications for its possible use as an ethanol-aversive drug." in: Adicciones, pp. 1226, (2019) (PubMed).
: "Inhibition of ALDH2 protects PC12 cells against formaldehyde-induced cytotoxicity: involving the protection of hydrogen sulphide." in: Clinical and experimental pharmacology & physiology, Vol. 44, Issue 5, pp. 595-601, (2017) (PubMed).
: "Comparative Proteomics Analysis Reveals L-Arginine Activates Ethanol Degradation Pathways in HepG2 Cells." in: Scientific reports, Vol. 6, pp. 23340, (2017) (PubMed).
: "Quantitative proteomics analysis reveals glutamine deprivation activates fatty acid β-oxidation pathway in HepG2 cells." in: Amino acids, Vol. 48, Issue 5, pp. 1297-307, (2017) (PubMed).
: "Mitochondrial aldehyde dehydrogenase 2 protects gastric mucosa cells against DNA damage caused by oxidative stress." in: Free radical biology & medicine, Vol. 93, pp. 165-76, (2016) (PubMed).
: "A novel mechanism for endogenous formaldehyde elevation in SAMP8 mouse." in: Journal of Alzheimer's disease : JAD, Vol. 40, Issue 4, pp. 1039-53, (2014) (PubMed).
: "Laser microdissection and two-dimensional difference gel electrophoresis reveal the role of a novel macrophage-capping protein in lymph node metastasis in gastric cancer." in: Journal of proteome research, Vol. 12, Issue 8, pp. 3780-91, (2013) (PubMed).
: "Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease." in: European heart journal, Vol. 33, Issue 13, pp. 1606-14, (2012) (PubMed).
Synonyme und alternative Namen zu ALDH2
aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1 (aldh2.1), aldehyde dehydrogenase 2 family (mitochondrial) L homeolog (aldh2.L), aldehyde dehydrogenase 2 family (mitochondrial) (aldh2), aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2), aldehyde dehydrogenase 2 (aldh2), aldehyde dehydrogenase (RHA1_RS43090), aldehyde dehydrogenase (NAD(+)) (aldH2), hypothetical protein (OE_RS03015), aldehyde dehydrogenase (aldH2), aldehyde dehydrogenase 2 family (mitochondrial) (Aldh2), aldehyde dehydrogenase 2, mitochondrial (Aldh2), Ahd-5, Ahd5, aldh-e2, ALDH-E2, aldh2, aldh2a, aldhi, ALDHI, aldm, ALDM, MGC80785, rf2b, zgc:63786Bezeichner auf Proteinebene für ALDH2
- aldehyde dehydrogenase 2
- aldehyde dehydrogenase 2 family (mitochondrial)
- aldehyde dehydrogenase 2 family (mitochondrial)a
- aldehyde dehydrogenase 2.1
- mitochondrial aldehyde dehydrogenase 2
- ALDH2B6
- mitochondrial aldehyde dehydrogenase RF2B
- aldehyde dehydrogenase
- aldehyde dehydrogenase (NAD(+))
- ALDH class 2
- ALDH-E2
- aldehyde dehydrogenase, mitochondrial
- aldehyde dehydrogenase, mitochondrial-like
- acetaldehyde dehydrogenase 2
- liver mitochondrial ALDH
- nucleus-encoded mitochondrial aldehyde dehydrogenase 2
- ALDH1
- aldehyde dehydrogenase 2, mitochondrial
- mitochondrial aldehyde dehydrogenase
- ALDHI
- AHD-M1
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