ALOX5 Produkte
(Arachidonate 5-Lipoxygenase (ALOX5))
Kategorien
This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
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Ausgewählte ALOX5 Kategorien
ALOX5 Antikörper
High quality antibodies with extensive validation data.
ALOX5 ELISA Kits
Reliable ELISA kits for a wide range of species.
ALOX5 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ALOX5 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7433525
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (5)
Kat. Nr.
ABIN513267
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN3023073
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene ALOX5 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6953906
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6964998
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6964995
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ALOX5 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1344921
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7393886
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7424545
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ALOX5 Produkten
: "Modulating effect of inositol hexaphosphate on arachidonic acid-dependent pathways in colon cancer cells." in: Prostaglandins & other lipid mediators, Vol. 131, pp. 41-48, (2018) (PubMed).: "BLT1 signalling protects the liver against acetaminophen hepatotoxicity by preventing excessive accumulation of hepatic neutrophils." in: Scientific reports, Vol. 6, pp. 29650, (2016) (PubMed).
: "Variants in ALOX5, ALOX5AP and LTA4H are not associated with atherosclerotic plaque phenotypes: the Athero-Express Genomics Study." in: Atherosclerosis, Vol. 239, Issue 2, pp. 528-38, (2015) (PubMed).
: "The protective effect of caffeic acid on global cerebral ischemia-reperfusion injury in rats." in: Behavioral and brain functions : BBF, Vol. 11, pp. 18, (2015) (PubMed).
: "Protective role of ellagitannins from Eucalyptus citriodora against ethanol-induced gastric ulcer in rats: impact on oxidative stress, inflammation and calcitonin-gene related peptide." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 22, Issue 1, pp. 5-15, (2015) (PubMed).
: "The comparative study of acetyl-11-keto-beta-boswellic acid (AKBA) and aspirin in the prevention of intestinal adenomatous polyposis in APC(Min/+) mice." in: Drug discoveries & therapeutics, Vol. 8, Issue 1, pp. 25-32, (2014) (PubMed).
: "5-Lipoxygenase inhibitors attenuate TNF-α-induced inflammation in human synovial fibroblasts." in: PLoS ONE, Vol. 9, Issue 9, pp. e107890, (2014) (PubMed).
: "Retinal upregulation of inflammatory and proangiogenic markers in a model of neonatal diabetic rats fed on a high-fat-diet." in: BMC ophthalmology, Vol. 13, Issue 1, pp. 14, (2013) (PubMed).
: "Leukotriene B4 type-1 receptor signaling promotes liver repair after hepatic ischemia/reperfusion injury through the enhancement of macrophage recruitment." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 8, pp. 3132-43, (2013) (PubMed).
: "ALOX5 promoter genotype, asthma severity and LTC production by eosinophils." in: Allergy, Vol. 61, Issue 1, pp. 97-103, (2005) (PubMed).
Synonyme und alternative Namen zu ALOX5
arachidonate 5-lipoxygenase (ALOX5), arachidonate 5-lipoxygenase (Alox5), arachidonate 5-lipoxygenase a (alox5a), arachidonate 5-lipoxygenase (AFUA_4G02770), arachidonate 5-lipoxygenase (AOR_1_1362014), Arachidonate 5-lipoxygenase (lox5), 5-LO, 5-LOX, 5LO, 5LPG, 5LX, AI850497, F730011J02, LOG5, lox5, LOX5A, si:dkey-194n13.2Bezeichner auf Proteinebene für ALOX5
- LOX-5
- arachidonic 5-lipoxygenase alpha-10 isoform
- arachidonic 5-lipoxygenase delta-10-13 isoform
- arachidonic 5-lipoxygenase delta-13 isoform
- arachidonic 5-lipoxygenase delta-p10 isoform
- arachidonic acid 5-lipoxygenase
- leukotriene A4 synthase
- 5-lipoxygenase
- 5 - Lipoxygenase
- 5-LO
- LOX2
- arachidonate 5-lipoxygenase
- Arachidonate 5-lipoxygenase
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