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ALOX5AP Produkte

(Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011].

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Ausgewählte ALOX5AP Kategorien

ALOX5AP Antikörper

High quality antibodies with extensive validation data.

ALOX5AP ELISA Kits

Reliable ELISA kits for a wide range of species.

ALOX5AP Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ALOX5AP Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, IHC, FACS, IF
Validierungen
  • (7)
Kat. Nr. ABIN185249
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN185717
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN392385
Menge 400 μL
Datenblatt Datenblatt

Empfohlene ALOX5AP ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6964996
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6730404
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1122348
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ALOX5AP Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1344923
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3096858
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3133653
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ALOX5AP Produkten

Schmider, Vaught, Bauer, Elliott, Godin, Ellis, Nigrovic, Soberman: "The organization of leukotriene biosynthesis on the nuclear envelope revealed by single molecule localization microscopy and computational analyses." in: PLoS ONE, Vol. 14, Issue 2, pp. e0211943, (2019) (PubMed).

Huang, Sharifpanah, Becker, Wartenberg, Sauer: "Impact of Arachidonic Acid and the Leukotriene Signaling Pathway on Vasculogenesis of Mouse Embryonic Stem Cells." in: Cells, tissues, organs, Vol. 201, Issue 5, pp. 319-32, (2016) (PubMed).

Elias, Ferré, Vilà, Muñoz, Casellas, Garcia, Molas, Agudo, Roca, Ruberte, Bosch, Franckhauser: "ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance." in: Diabetes, Vol. 65, Issue 8, pp. 2139-50, (2016) (PubMed).

van der Laan, Foroughi Asl, van den Borne, van Setten, van der Perk, van de Weg, Schoneveld, de Kleijn, Michoel, Björkegren, den Ruijter, Asselbergs, de Bakker, Pasterkamp: "Variants in ALOX5, ALOX5AP and LTA4H are not associated with atherosclerotic plaque phenotypes: the Athero-Express Genomics Study." in: Atherosclerosis, Vol. 239, Issue 2, pp. 528-38, (2015) (PubMed).

Zhang, Yu, Ni, Shen, Das: "Growth inhibitory effect of polyunsaturated fatty acids (PUFAs) on colon cancer cells via their growth inhibitory metabolites and fatty acid composition changes." in: PLoS ONE, Vol. 10, Issue 4, pp. e0123256, (2015) (PubMed).

Perisic, Hedin, Razuvaev, Lengquist, Osterholm, Folkersen, Gillgren, Paulsson-Berne, Ponten, Odeberg, Hedin: "Profiling of atherosclerotic lesions by gene and tissue microarrays reveals PCSK6 as a novel protease in unstable carotid atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 33, Issue 10, pp. 2432-43, (2013) (PubMed).

Finkensieper, Kieser, Bekhite, Richter, Mueller, Graebner, Figulla, Sauer, Wartenberg: "The 5-lipoxygenase pathway regulates vasculogenesis in differentiating mouse embryonic stem cells." in: Cardiovascular research, Vol. 86, Issue 1, pp. 37-44, (2010) (PubMed).

Maier, Tausch, Hoernig, Coste, Schmidt, Angioni, Metzner, Groesch, Pergola, Steinhilber, Werz, Geisslinger: "Celecoxib inhibits 5-lipoxygenase." in: Biochemical pharmacology, Vol. 76, Issue 7, pp. 862-72, (2008) (PubMed).

Kaaman, Rydén, Axelsson, Nordström, Sicard, Bouloumié, Langin, Arner, Dahlman: "ALOX5AP expression, but not gene haplotypes, is associated with obesity and insulin resistance." in: International journal of obesity (2005), Vol. 30, Issue 3, pp. 447-52, (2006) (PubMed).

Helgadottir, Manolescu, Thorleifsson, Gretarsdottir, Jonsdottir, Thorsteinsdottir, Samani, Gudmundsson, Grant, Thorgeirsson, Sveinbjornsdottir, Valdimarsson, Matthiasson, Johannsson, Gudmundsdottir et al.: "The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. ..." in: Nature genetics, Vol. 36, Issue 3, pp. 233-9, (2004) (PubMed).

Synonyme und alternative Namen zu ALOX5AP

arachidonate 5-lipoxygenase-activating protein (alox5ap), arachidonate 5-lipoxygenase activating protein (ALOX5AP), arachidonate 5-lipoxygenase activating protein (alox5ap), arachidonate 5-lipoxygenase activating protein (Alox5ap), al5ap, Alox5ap, ALOX5AP, fj65d02, flap, Flap, FLAP, wu:fj65d02, zgc:63982

Bezeichner auf Proteinebene für ALOX5AP

  • arachidonate 5-lipoxygenase-activating protein
  • Arachidonate 5-lipoxygenase-activating protein
  • MK-886-binding protein
  • arachidonate 5 lipoxygenase activating protein
  • 5-lipoxygenase-activating protein FLAP
  • FLAP
  • arachidonate 5-lipoxygenase activating protein
  • 5-lipoxygenase-activating protein
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