alpha Adaptin Produkte
(Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))
Kategorien
This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008].
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Ausgewählte alpha Adaptin Kategorien
alpha Adaptin Antikörper
High quality antibodies with extensive validation data.
alpha Adaptin Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene alpha Adaptin Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (1)
- (5)
Kat. Nr.
ABIN5539681
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Dog, Human, Mouse, Rat
Applikation
WB, IP, IF, BI, IHC (f)
Validierungen
- (6)
- (5)
Kat. Nr.
ABIN968009
Menge
150 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN6136952
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene alpha Adaptin ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6212658
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene alpha Adaptin Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7121699
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345241
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3088890
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren alpha Adaptin Produkten
: "Quantitative proteomics reveals reduction of endocytic machinery components in gliomas." in: EBioMedicine, Vol. 46, pp. 32-41, (2020) (PubMed).: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).
: "Constitutive clathrin-mediated endocytosis of CTLA-4 persists during T cell activation." in: The Journal of biological chemistry, Vol. 287, Issue 12, pp. 9429-40, (2012) (PubMed).
: "Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration." in: The Journal of biological chemistry, Vol. 284, Issue 18, pp. 12447-58, (2009) (PubMed).
: "Endocytosis of synaptotagmin 1 is mediated by a novel, tryptophan-containing motif." in: Traffic (Copenhagen, Denmark), Vol. 4, Issue 7, pp. 468-78, (2003) (PubMed).
: "Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics." in: The Journal of cell biology, Vol. 158, Issue 5, pp. 855-62, (2002) (PubMed).
: "Numb is an endocytic protein." in: The Journal of cell biology, Vol. 151, Issue 6, pp. 1345-52, (2001) (PubMed).
: "The AP2 binding site of synaptotagmin 1 is not an internalization signal but a regulator of endocytosis." in: The Journal of cell biology, Vol. 154, Issue 4, pp. 857-66, (2001) (PubMed).
: "The tyrosine kinase ACK1 associates with clathrin-coated vesicles through a binding motif shared by arrestin and other adaptors." in: The Journal of biological chemistry, Vol. 276, Issue 21, pp. 18392-8, (2001) (PubMed).
: "The huntingtin interacting protein HIP1 is a clathrin and alpha-adaptin-binding protein involved in receptor-mediated endocytosis." in: Human molecular genetics, Vol. 10, Issue 17, pp. 1807-17, (2001) (PubMed).
Synonyme und alternative Namen zu alpha Adaptin
adaptor related protein complex 2 alpha 1 subunit (AP2A1), adaptor related protein complex 2 alpha 1 subunit (ap2a1), adaptor-related protein complex 2, alpha 1 subunit (Ap2a1), AP-2 complex subunit alpha-1 (EDI_093420), AP-2 complex subunit alpha-1 (EDI_259990), adaptor related protein complex 2 alpha 1 subunit (Ap2a1), ADTAA, adtaa, Adtaa, AP2-ALPHA, ap2-alpha, AP2A1, CLAPA1, clapa1Bezeichner auf Proteinebene für alpha Adaptin
- 100 kDa coated vesicle protein A
- AP-2 complex subunit alpha-1
- adapter-related protein complex 2 alpha-1 subunit
- adaptin, alpha A
- adaptor protein complex AP-2 subunit alpha-1
- alpha-adaptin A
- alpha1-adaptin
- clathrin assembly protein complex 2 alpha-A large chain
- clathrin-associated/assembly/adaptor protein, large, alpha 1
- plasma membrane adaptor HA2/AP2 adaptin alpha A subunit
- adaptor protein complex AP-2, alpha 1 subunit
- adaptor-related protein complex 2, alpha 1 subunit
- AP-2 complex subunit alpha-1-like
- adaptor-related protein complex AP-2, alpha 1 subunit
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