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AMACR Produkte

(alpha-Methylacyl-CoA Racemase (AMACR))
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011].

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Ausgewählte AMACR Kategorien

AMACR Antikörper

High quality antibodies with extensive validation data.

AMACR ELISA Kits

Reliable ELISA kits for a wide range of species.

AMACR Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene AMACR Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, StM
Validierungen
  • (7)
Kat. Nr. ABIN6939431
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p), FACS
Validierungen
  • (5)
Kat. Nr. ABIN654069
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, StM
Validierungen
  • (5)
Kat. Nr. ABIN6939430
Menge 100 μg
Datenblatt Datenblatt

Empfohlene AMACR ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6964773
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953651
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN4993314
Menge 96 tests
Datenblatt Datenblatt

Empfohlene AMACR Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7121802
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1344965
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7409431
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren AMACR Produkten

Drusian, Nigro, Mannella, Pagliarini, Pema, Costa, Benigni, Larcher, Chiaravalli, Gaude, Montorsi, Capitanio, Musco, Frezza, Boletta: "mTORC1 Upregulation Leads to Accumulation of the Oncometabolite Fumarate in a Mouse Model of Renal Cell Carcinoma." in: Cell reports, Vol. 24, Issue 5, pp. 1093-1104.e6, (2018) (PubMed).

Wang, Tian, Xiao, Zhang, Sun, Tang: "A metanephric adenoma of the kidney associated with polycythemia: A case report." in: Oncology letters, Vol. 11, Issue 1, pp. 352-354, (2016) (PubMed).

Chen, Watson, Marengo, Decker, Coleman, Nelson, Sikes: "Gene expression in the LNCaP human prostate cancer progression model: progression associated expression in vitro corresponds to expression changes associated with prostate cancer progression in vivo." in: Cancer letters, Vol. 244, Issue 2, pp. 274-88, (2006) (PubMed).

Epstein, Herawi: "Prostate needle biopsies containing prostatic intraepithelial neoplasia or atypical foci suspicious for carcinoma: implications for patient care." in: The Journal of urology, Vol. 175, Issue 3 Pt 1, pp. 820-34, (2006) (PubMed).

Ferdinandusse, Denis, Clayton, Graham, Rees, Allen, McLean, Brown, Vreken, Waterham, Wanders: "Mutations in the gene encoding peroxisomal alpha-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy." in: Nature genetics, Vol. 24, Issue 2, pp. 188-91, (2000) (PubMed).

Kotti, Savolainen, Helander, Yagi, Novikov, Kalkkinen, Conzelmann, Hiltunen, Schmitz: "In mouse alpha -methylacyl-CoA racemase, the same gene product is simultaneously located in mitochondria and peroxisomes." in: The Journal of biological chemistry, Vol. 275, Issue 27, pp. 20887-95, (2000) (PubMed).

Synonyme und alternative Namen zu AMACR

alpha-methylacyl-CoA racemase (AMACR), alpha-methylacyl-CoA racemase (mcr), PROBABLE ALPHA-METHYLACYL-COA RACEMASE MCR (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase) (mcr), alpha-methylacyl-CoA racemase (BPSL0064), Alpha-methylacyl-CoA racemase (Maqu_2037), alpha-methylacyl-CoA racemase (UREG_03852), alpha-methylacyl-CoA racemase (MCYG_01809), alpha-methylacyl-CoA racemase (amacr), alpha-methylacyl-CoA racemase L homeolog (amacr.L), alpha-methylacyl-CoA racemase (MGYG_04259), alpha-methylacyl-CoA racemase (NCU04099), alpha-methylacyl-CoA racemase (Amacr), AMACR, amacr, AMACRD, CBAS4, Da1-8, DKFZp469O1232, Macr1, Marc1, MGC89832, NCU04099.1, RACE, RM

Bezeichner auf Proteinebene für AMACR

  • alpha-methylacyl-CoA racemase
  • Alpha-methylacyl-CoA racemase
  • alpha-methylacyl-CoA racemase-like
  • amacr protein
  • 2-methylacyl-CoA racemase
  • 2-arylpropionyl-CoA epimerase
  • alpha-methylacyl-Coenzyme A racemase
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