Aminoacylase 1 Produkte
(Aminoacylase 1 (ACY1))
Kategorien
This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Nov 2010].
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Ausgewählte Aminoacylase 1 Kategorien
Aminoacylase 1 Antikörper
High quality antibodies with extensive validation data.
Aminoacylase 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Aminoacylase 1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Aminoacylase 1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IP, IHC (p)
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN559777
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7434791
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Dog, Human, Mouse, Rat
Applikation
WB, IHC, FACS, IHC (p)
Validierungen
- (6)
Kat. Nr.
ABIN1496452
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Aminoacylase 1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6953660
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4881733
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6730070
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Aminoacylase 1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7121810
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7121809
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1305823
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Aminoacylase 1 Produkten
: "Profiling of antibody production against xenograft-released proteins by protein microarrays discovers prostate cancer markers." in: Journal of proteome research, Vol. 11, Issue 2, pp. 728-35, (2012) (PubMed).: "The molecular basis of aminoacylase 1 deficiency." in: Biochimica et biophysica acta, Vol. 1812, Issue 6, pp. 685-90, (2011) (PubMed).
: "Acylase 1 expression in rat intestinal crypt--villus axis." in: Cell biology international, Vol. 31, Issue 9, pp. 966-73, (2007) (PubMed).
: "Aminoacylase I deficiency: a novel inborn error of metabolism." in: Biochemical and biophysical research communications, Vol. 338, Issue 3, pp. 1322-6, (2005) (PubMed).
Synonyme und alternative Namen zu Aminoacylase 1
aminoacylase 1 (ACY1), aminoacylase 1 (acy1), aminoacylase 1, gene 1 S homeolog (acy1.1.S), aminoacylase 1, gene 1 (acy1.1), aminoacylase 1 (Acy1), 1110014J22Rik, ACY-1, Acy-1, acy1, ACY1, Acy1a, Acy1b, acy1d, ACY1D, acylase, si:zfos-226g1.1, zgc:55605, zgc:76955Bezeichner auf Proteinebene für Aminoacylase 1
- aminoacylase-1
- aminoacylase 1
- N-acyl-L-amino-acid amidohydrolase
- acylase
- ACY IA
- ACY IB
- ACY-1A
- ACY-1B
- aminoacylase-1A
- aminoacylase-1B
- ACY-1
- N-acylamino acid aminohydrolase (Aminoacylase 1)
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