ANGL4 Protein (AA 28-403, partial) (GST tag)
ANGL4
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS
1 image
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- Target
- ANGL4 (Angiopoietin-Related Protein 4 (ANGL4))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 28-403, partial
- Spezies
- Human
- Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses ANGL4 Protein ist gelabelt mit GST tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- VQSKSPRFAS WDEMNVLAHG LLQLGQGLRE HAERTRSQLS ALERRLSACG SACQGTEGST DLPLAPESRV DPEVLHSLQT QLKAQNSRIQ QLFHKVAQQQ RHLEKQHLRI QHLQSQFGLL DHKHLDHEVA KPARRKRLPE MAQPVDPAHN VSRLHRLPRD CQELFQVGER QSGLFEIQPQ GSPPFLVNCK MTSDGGWTVI QRRHDGSVDF NRPWEAYKAG FGDPHGEFWL GLEKVHSITG DRNSRLAVQL RDWDGNAELL QFSVHLGGED TAYSLQLTAP VAGQLGATTV PPSGLSVPFS TWDQDHDLRR DKNCAKSLSG GWWFGTCSHS NLNGQYFRSI PQQRQKLKKG IFWKTWRGRY YPLQATTMLI QPMAAE
- Aufreinigung
- SDS-PAGE
- Reinheit
- > 90 %
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Lagerung
- -80 °C,4 °C,-20 °C
- Informationen zur Lagerung
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- ANGL4 (Angiopoietin-Related Protein 4 (ANGL4))
- Andere Bezeichnung
- ANGL4
- Hintergrund
- Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation .
- Molekulargewicht
- 69.9 kDa
- UniProt
- Q9BY76
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