ANTXR1 Produkte
(anthrax Toxin Receptor 1 (ANTXR1))
Kategorien
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008].
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Ausgewählte ANTXR1 Kategorien
ANTXR1 Antikörper
High quality antibodies with extensive validation data.
ANTXR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
ANTXR1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ANTXR1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN392154
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IF
Validierungen
- (2)
Kat. Nr.
ABIN185280
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC
Validierungen
- (2)
Kat. Nr.
ABIN205769
Menge
0.1 mg
Datenblatt
Datenblatt
Empfohlene ANTXR1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6964899
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1122056
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Validierungen
Kat. Nr.
ABIN1122057
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ANTXR1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7121857
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345161
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345159
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ANTXR1 Produkten
: "Structural basis for anthrax toxin receptor 1 recognition by Seneca Valley Virus." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 46, pp. E10934-E10940, (2019) (PubMed).: "Isolated tumor endothelial cells maintain specific character during long-term culture." in: Biochemical and biophysical research communications, Vol. 394, Issue 4, pp. 947-54, (2010) (PubMed).
: "The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin." in: Cell, Vol. 124, Issue 6, pp. 1141-54, (2006) (PubMed).
: "Anthrax toxin receptor 1/tumor endothelium marker 8 mediates cell spreading by coupling extracellular ligands to the actin cytoskeleton." in: The Journal of biological chemistry, Vol. 281, Issue 32, pp. 23227-36, (2006) (PubMed).
: "Receptor-specific requirements for anthrax toxin delivery into cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 37, pp. 13278-83, (2005) (PubMed).
: "TEM8 expression stimulates endothelial cell adhesion and migration by regulating cell-matrix interactions on collagen." in: Experimental cell research, Vol. 305, Issue 1, pp. 133-44, (2005) (PubMed).
: "NALP1 is a transcriptional target for cAMP-response-element-binding protein (CREB) in myeloid leukaemia cells." in: The Biochemical journal, Vol. 384, Issue Pt 2, pp. 281-6, (2004) (PubMed).
: "TEM8 interacts with the cleaved C5 domain of collagen alpha 3(VI)." in: Cancer research, Vol. 64, Issue 3, pp. 817-20, (2004) (PubMed).
: "Action of recombinant human apoptotic endonuclease G on naked DNA and chromatin substrates: cooperation with exonuclease and DNase I." in: The Journal of biological chemistry, Vol. 276, Issue 51, pp. 48404-9, (2001) (PubMed).
: "Mitochondrial endonuclease G is important for apoptosis in C. elegans." in: Nature, Vol. 412, Issue 6842, pp. 90-4, (2001) (PubMed).
Synonyme und alternative Namen zu ANTXR1
anthrax toxin receptor 1 (ANTXR1), anthrax toxin receptor 1 (Antxr1), 2310008J16Rik, 2810405N18Rik, Antrx1, ANTXR1, ATR, TEM8, Tem8Bezeichner auf Proteinebene für ANTXR1
- anthrax toxin receptor 1
- tumor endothelial marker 8
- anthrax toxin receptor 1-like
- 2310008J16Rik
- 2810405N18Rik
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