NIPBL Antikörper (AA 344-356)

Produktnummer ABIN100654

Produktdetails anti-NIPBL Antikörper

Target: NIPBL (Nipped-B like Protein (NIPBL))

Bindungsspezifität: AA 344-356

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser NIPBL Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktmerkmale: Concentration Definition: by UV absorbance at 280 nm

Sterilität: Sterile filtered

Immunogen: This affinity-purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 344-356 of Human IDN3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This affinity purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect bands at 316 kDa in size corresponding to IDN3 by western blotting in the appropriate cell lysate or extract.  Splice variants for this protein may show molecular weights of 304 kDa and 122 kDa.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.6 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu NIPBL

Target: NIPBL (Nipped-B like Protein (NIPBL))

Andere Bezeichnung: IDN3 (NIPBL Produkte)

Synonyme: CDLS antikoerper, CDLS1 antikoerper, IDN3 antikoerper, IDN3-B antikoerper, Scc2 antikoerper, SCC2W antikoerper, scc2 antikoerper, nipbl antikoerper, scc2-2 antikoerper, NIPBL antikoerper, nipbla antikoerper, wu:fi33d08 antikoerper, 4921518A06Rik antikoerper, 4933421G18Rik antikoerper, C79399 antikoerper, Idn3 antikoerper, NIPBL, cohesin loading factor antikoerper, Nipped-B homolog-like antikoerper, NIPBL, cohesin loading factor S homeolog antikoerper, nipped-B homolog b (Drosophila) antikoerper, nipped-B-like protein A antikoerper, Nipped-B homolog (Drosophila) antikoerper, NIPBL antikoerper, NIPBLL antikoerper, nipbl.S antikoerper, LOC427439 antikoerper, nipblb antikoerper, LOC100164947 antikoerper, nipbl antikoerper, Nipbl antikoerper

Hintergrund: IDN3 (also known as Colon tumor susceptibility 2, DKFZp434L1319, FLJ13648, Mis 4, Scc-2, Delangin and Sister chromatid cohesion protein) is the mammalian homologue of Scc2 in S. cerevisiae and Mis4 in S. pombe. In yeast, this factor was originally identified genetically as being involved in sister chromatid cohesion; subsequent work has determined that it is not involved in cohesion directly but is required for the loading of cohesins onto chromatin during S phase. It shares 37% sequence identity with Nipped-B gene product of Drosophila, which facilitates enhancer-promoter communication of remote enhancers. The Drosophila protein is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair.  IDN3 is a nuclear protein that is widely expressed and found at the highest levels in heart, skeletal muscle, fetal and adult liver, and fetal and adult kidney. The protein is also found, albeit at lower levels of expression in thymus, placenta, peripheral leukocyte and small intestine.  Multiple isoforms of the protein have been reported.
Synonyms: CDLS antibody, Colon tumor susceptibility 2 antibody, Delangin antibody, DKFZp434L1319 antibody, FLJ11203 antibody

Gen-ID: 25836, 4760549

UniProt: Q6KC79

Pathways: Sensory Perception of Sound, Stem Cell Maintenance