CD63 Antikörper (Biotin)
-
- Target Alle CD63 Antikörper anzeigen
- CD63
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser CD63 Antikörper ist konjugiert mit Biotin
-
Applikation
- Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- Spezifität
- The antibody MEM-259 reacts with an extracellular/luminal epitope of CD63 (LAMP-3), a 40-60 kDa tetraspan glycoprotein expressed by granulocytes, platelets, T cells, monocytes/macrophages and endothelial cells. Cell surface exposition of CD63 is usually activation-dependent.
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
- Immunogen
- HPB-ALL T cell line
- Klon
- MEM-259
- Isotyp
- IgG1
- Top Product
- Discover our top product CD63 Primärantikörper
-
-
- Applikationshinweise
- Flow cytometry: Recommended dilution: 1-3 μg/mL, positive material: activated platelets, neutrophils and basophils.
- Kommentare
-
The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
-
Do not freeze.
Avoid prolonged exposure to light. - Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
-
-
Clues to Non-Invasive Implantation Window Monitoring: Isolation and Characterisation of Endometrial Exosomes." in: Cells, Vol. 8, Issue 8, (2020) (PubMed).
: "Pimecrolimus Is a Potent Inhibitor of Allergic Reactions to Hymenopteran Venom Extracts and Birch Pollen Allergen In Vitro." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142953, (2015) (PubMed).
: "The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing." in: EMBO reports, Vol. 5, Issue 9, pp. 883-8, (2004) (PubMed).
: "
-
Clues to Non-Invasive Implantation Window Monitoring: Isolation and Characterisation of Endometrial Exosomes." in: Cells, Vol. 8, Issue 8, (2020) (PubMed).
-
- Target
- CD63
- Andere Bezeichnung
- CD63 (CD63 Produkte)
- Synonyme
- C75951 antikoerper, ME491 antikoerper, Tspan30 antikoerper, LAMP-3 antikoerper, MLA1 antikoerper, OMA81H antikoerper, TSPAN30 antikoerper, TSP29FA antikoerper, CD63 antigen antikoerper, CD63 molecule antikoerper, Cd63 molecule antikoerper, Cd63 antikoerper, CD63 antikoerper
- Hintergrund
- CD63 Molecule,CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. It is also present in the plasma membrane, usually following cell activation. Hence, it has become an widely used basophil activation marker. In mast cells, however, CD63 exposition does not need their activation. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell costimulation molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas.,OMA81H, Granulophysin, Tetraspanin-30, Tspan-30, MLA1, ME491, LAMP-3, OMA81H, TSPAN30
- Gen-ID
- 967
- UniProt
- P08962
-