AFAP1L1 Antikörper (N-Term)

Produktnummer ABIN1031218

Produktdetails anti-AFAP1L1 Antikörper

Target: AFAP1L1 (Actin Filament Associated Protein 1-Like 1 (AFAP1L1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AFAP1L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: At least four isoforms of AFAP1L1 are known to exist. This antibody is predicted to not cross-react with other AFAP family members.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: AFAP1L1 antibody was raised against a AA 19 synthetic peptide near the amino terminus of human AFAP1L1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: AFAP1L1 antibody can be used for detection of AFAP1L1 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. Optimal dilutions for each application to be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: AFAP1L antibody can be stored at 4 °C for three months and -20 °C, stable for up to one year.

Haltbarkeit: 12 months

Details zu AFAP1L1

Target: AFAP1L1 (Actin Filament Associated Protein 1-Like 1 (AFAP1L1))

Abstract: AFAP1L1 Produkte

Hintergrund: Synonym:
Actin filament associated protein 1-like 1

The actin filament-associated protein 1 (AFAP1)-like 1 protein is one of three members in the AFAP1 family of adaptor proteins. Like AFAP1, AFAP1L1 is an actin binding protein that has a role in actin cytoskeleton arrangement, but AFAP1L1 is thought to have a unique function distinct from AFAP1. AFAP1L1 colocalizes with cortactin and localizes to invadosomes, highly dynamic, actin-rich adhesion structures harboring metalloproteases, suggesting that AFAP1L1 affects invadosome formation . Recent reports suggest that AFAP1L1 can be used as a prognostic marker for spindle cell sarcomas.

Gen-ID: 134265

NCBI Accession: NP_689619