Progerin (AA 604-611) Antikörper

Produktnummer ABIN1042661

Produktdetails

Target: Progerin

Bindungsspezifität: AA 604-611

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Applikation: Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB), Immunoprecipitation (IP), ELISA

Sequenz: GAQSPQNC

Spezifität: Specifically recognizes Progerin (LaminAdelta50) and does not cross-react with endogenous prelamin A

Aufreinigung: Protein G

Immunogen: Synthetic peptide conjugated to KLH derived from within residues 604 - 611 (GAQSPQNC) at the C terminus of Human Progerin

Klon: 13A4D4

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal antibody dilution should be determined by titration, however as a guideline try,WB: 1/500. Detects a band of approximately 70 kDa

Kommentare:

Myeloma, fusion partners: X63-Ag8.653

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Purified antibody (from supernatant) containing PBS + 0.1 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Referenzen

Liu, Barkho, Ruiz, Diep, Qu, Yang, Panopoulos, Suzuki, Kurian, Walsh, Thompson, Boue, Fung, Sancho-Martinez, Zhang, Yates, Izpisua Belmonte: "Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome." in: Nature, Vol. 472, Issue 7342, pp. 221-5, (2011) (PubMed).

Antigendetails

Target: Progerin

Andere Bezeichnung: Progerin 

Gen-ID: 24380

OMIM: 150330