TUBGCP2 Antikörper (AA 2-194)

Produktnummer ABIN1043030

Produktdetails anti-TUBGCP2 Antikörper

Target: TUBGCP2 (Tubulin, gamma Complex Associated Protein 2 (TUBGCP2))

Bindungsspezifität: AA 2-194

Reaktivität: Human, Maus, Ratte, Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TUBGCP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: The mouse monoclonal antibody GCP2-01 recognizes gamma-tubulin complex component 2 (GCP2), a 95-103 kDa intracellular protein. It recognizes also phosphorylated GCP2.

Kreuzreaktivität (Details): Human, Porcine, Mouse, Rat

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: GST-fusion protein containing amino acids 2-194 of mouse GCP2

Klon: GCP2-01

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Western blotting: Recommended dilution: 1-2 μg/mL, reducing conditions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Referenzen für anti-TUBGCP2 Antikörper (ABIN1043030)

Dráberová, DAgostino, Caracciolo, Sládková, Sulimenko, Sulimenko, Sobol, Maounis, Tzelepis, Mahera, K?en, Legido, Giordano, Mörk, Hozák, Dráber, Katsetos: "Overexpression and Nucleolar Localization of ?-Tubulin Small Complex Proteins GCP2 and GCP3 in Glioblastoma." in: Journal of neuropathology and experimental neurology, Vol. 74, Issue 7, pp. 723-42, (2015) (PubMed).

Ho?ejší, Vinopal, Sládková, Dráberová, Sulimenko, Sulimenko, Vosecká, Philimonenko, Hozák, Katsetos, Dráber: "Nuclear ?-tubulin associates with nucleoli and interacts with tumor suppressor protein C53." in: Journal of cellular physiology, Vol. 227, Issue 1, pp. 367-82, (2011) (PubMed).

Details zu TUBGCP2

Target: TUBGCP2 (Tubulin, gamma Complex Associated Protein 2 (TUBGCP2))

Andere Bezeichnung: Gamma-tubulin complex component 2 (TUBGCP2 Produkte)

Synonyme: GCP-2 antikoerper, GCP2 antikoerper, Grip103 antikoerper, SPBC97 antikoerper, Spc97p antikoerper, h103p antikoerper, hGCP2 antikoerper, hSpc97 antikoerper, 1700022B05Rik antikoerper, Adam8 antikoerper, tubulin gamma complex associated protein 2 antikoerper, tubulin, gamma complex associated protein 2 antikoerper, TUBGCP2 antikoerper, Tubgcp2 antikoerper

Hintergrund: Tubulin gamma complex associated protein 2,Gamma tubulin complex component 2 (GCP2) is 95-103 kDa protein which associates with two molecules of gamma tubulin and one molecule of gamma tubulin complex component 3 (GCP3), to form the gamma tubulin small complexes (gammaTuSCs). These complexes interact with GCP4, 5, and 6 to form the gamma tubulin ring complexes (gammaTuRCs), which are embedded in the microtubule organizing center matrix where they nucleate microtubules. The gammaTuRCs are also involved in the regulation of microtubule plus and minus end dynamics. Components of gamma tubulin complexes are highly conservative in eukaryotes.,GCP-2, GTCC2, GTC2

Gen-ID: 10844

UniProt: Q9BSJ2

Pathways: M Phase, SARS-CoV-2 Protein Interaktom