aHSP Antikörper

Produktnummer ABIN1043695

Produktdetails anti-aHSP Antikörper

Target: aHSP (alpha Hemoglobin Stabilizing Protein (aHSP))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser aHSP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Fluorescence Microscopy (FM)

Spezifität: Anti-AHSP Antibody is directed against the human AHSP protein. The product was prepared from monospecific antiserum by delipidation and defibrination. A BLAST analysis was used to suggest cross reactivity with human and mouse. Cross-reactivity with AHSP from other sources have not been determined.

Produktmerkmale: AHSP Antibody detects Alpha hemoglobin stabilizing protein (AHSP). AHSP acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. AHSP binds free a-globin to promote its folding and inhibit its ability to produce damaging reactive oxygen species. Reduced AHSP levels correlate with increased severity of b-thalassemia in some human cohorts.

Immunogen: Anti-AHSP Antibody was produced from whole rabbit serum prepared by repeated immunizations with the full length human AHSP protein.
Immunogen Type: RecombinantProtein

Anwendungsinformationen

Applikationshinweise: Anti-AHSP Antibody is suitable for western blotting, immunohistochemistry (Formalin-fixed paraffin-embedded sections), immunofluorescence microscopy using paraformaldehyde-fixed primary cardiomyocyte cultures and ELISA. Specific conditions for reactivity should be optimized by the end user.

Kommentare:

Gene Name: AHSP

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL

Konzentration: 86 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Haltbarkeit: 12 months

Referenzen für anti-aHSP Antikörper (ABIN1043695)

Nasimuzzaman, Khandros, Wang, Kong, Zhao, Weiss, Rivella, Weiss, Persons: "Analysis of alpha hemoglobin stabilizing protein overexpression in murine β-thalassemia." in: American journal of hematology, Vol. 85, Issue 10, pp. 820-2, (2010) (PubMed).

Details zu aHSP

Target: aHSP (alpha Hemoglobin Stabilizing Protein (aHSP))

Andere Bezeichnung: AHSP (aHSP Produkte)

Synonyme: AHSP antikoerper, ERAF antikoerper, EDRF antikoerper, Eraf antikoerper, alpha hemoglobin stabilizing protein antikoerper, alpha-hemoglobin-stabilizing protein-like antikoerper, AHSP antikoerper, Ahsp antikoerper, LOC100620111 antikoerper

Hintergrund: AHSP Antibody detects Alpha hemoglobin stabilizing protein (AHSP). AHSP acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. AHSP binds free a-globin to promote its folding and inhibit its ability to produce damaging reactive oxygen species. Reduced AHSP levels correlate with increased severity of b-thalassemia in some human cohorts.
Synonyms: Alpha-hemoglobin-stabilizing protein (AHSP), Erythroid differentiation-related factor, Erythroid-associated factor, EDRF, ERAF

Gen-ID: 51327

NCBI Accession: NP_057717

UniProt: Q9NZD4