BIN3 Antikörper
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- Target Alle BIN3 Antikörper anzeigen
- BIN3 (Bridging Integrator 3 (BIN3))
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Reaktivität
- Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser BIN3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- Hersteller Produkt- Nr.
- 200-301-e64
- Hersteller
- Rockland
- Verwendungszweck
- BIN3 Antibody
- Kreuzreaktivität (Details)
- BIN3 antibody is specific for human BIN3 protein.
- Produktmerkmale
- Synonyms: mouse anti-BIN3 Antibody, Bridging integrator 3, BIN-3, BIN 3, BIN3 antibody, anti-BIN-3 antibody
- Aufreinigung
- Anti-BIN3 was purified from clarified mouse ascetic fluid by Protein A chromatography followed by extensive dialysis against the buffer stated above.
- Sterilität
- Sterile filtered
- Immunogen
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Immunogen: Anti-BIN3 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with a full length human BIN3 recombinant protein followed by hybridoma development.
Immunogen Type: Recombinant Protein
- Klon
- 3A4
- Isotyp
- IgG1
- Top Product
- Discover our top product BIN3 Primärantikörper
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- Applikationshinweise
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Application Note: Anti-BIN3 antibody has been tested for use in ELISA, Western Blot, and IP. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 1:500-1:1500
Immunoprecipitation Dilution: 10-100 μL
ELISA Dilution: 1:5000-1:50000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.0 mg/mL
- Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide - Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- Haltbarkeit
- 12 months
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Human BIN3 complements the F-actin localization defects caused by loss of Hob3p, the fission yeast homolog of Rvs161p." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21670-7, (2001) (PubMed).
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Human BIN3 complements the F-actin localization defects caused by loss of Hob3p, the fission yeast homolog of Rvs161p." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21670-7, (2001) (PubMed).
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- Target
- BIN3 (Bridging Integrator 3 (BIN3))
- Andere Bezeichnung
- BIN3 (BIN3 Produkte)
- Hintergrund
- Background: BIN-3 encodes an evolutionarily conserved and ubiquitously expressed member of the BAR superfamily of curved membrane and GTPase-binding proteins implicated in signal transduction and vesicular trafficking. In humans, Bin3 maps to chromosome 8p21.3, a region widely implicated in cancer suppression that is often deleted in non-Hodgkin's lymphomas and various epithelial tumors. Study in mouse suggests that homozygous inactivation of Bin3 causes cataracts and an increased susceptibility to lymphomas during aging.
- Gen-ID
- 55909
- NCBI Accession
- NP_061158
- UniProt
- Q9NQY0
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