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BIN3 Antikörper

Rockland 200-301-e64 BIN3 Reaktivität: Maus WB, ELISA, IP Wirt: Maus Monoclonal 3A4 unconjugated
Rockland
Produktnummer ABIN1043741
Hersteller Produkt- Nr.: 200-301-e64
  • Target Alle BIN3 Antikörper anzeigen
    BIN3 (Bridging Integrator 3 (BIN3))
    Reaktivität
    • 37
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 27
    • 10
    Maus
    Klonalität
    • 29
    • 8
    Monoklonal
    Konjugat
    • 22
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BIN3 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 15
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    Hersteller Produkt- Nr.
    200-301-e64
    Hersteller
    Rockland
    Verwendungszweck
    BIN3 Antibody
    Kreuzreaktivität (Details)
    BIN3 antibody is specific for human BIN3 protein.
    Produktmerkmale
    Synonyms: mouse anti-BIN3 Antibody, Bridging integrator 3, BIN-3, BIN 3, BIN3 antibody, anti-BIN-3 antibody
    Aufreinigung
    Anti-BIN3 was purified from clarified mouse ascetic fluid by Protein A chromatography followed by extensive dialysis against the buffer stated above.
    Sterilität
    Sterile filtered
    Immunogen

    Immunogen: Anti-BIN3 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with a full length human BIN3 recombinant protein followed by hybridoma development.

    Immunogen Type: Recombinant Protein

    Klon
    3A4
    Isotyp
    IgG1
    Top Product
    Discover our top product BIN3 Primärantikörper
  • Applikationshinweise

    Application Note: Anti-BIN3 antibody has been tested for use in ELISA, Western Blot, and IP. Specific conditions for reactivity should be optimized by the end user.

    Western Blot Dilution: 1:500-1:1500

    Immunoprecipitation Dilution: 10-100 μL

    ELISA Dilution: 1:5000-1:50000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/mL
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    Haltbarkeit
    12 months
  • Routhier, Burn, Abbaszade, Summers, Albright, Prendergast: "Human BIN3 complements the F-actin localization defects caused by loss of Hob3p, the fission yeast homolog of Rvs161p." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21670-7, (2001) (PubMed).

  • Target
    BIN3 (Bridging Integrator 3 (BIN3))
    Andere Bezeichnung
    BIN3 (BIN3 Produkte)
    Hintergrund
    Background: BIN-3 encodes an evolutionarily conserved and ubiquitously expressed member of the BAR superfamily of curved membrane and GTPase-binding proteins implicated in signal transduction and vesicular trafficking. In humans, Bin3 maps to chromosome 8p21.3, a region widely implicated in cancer suppression that is often deleted in non-Hodgkin's lymphomas and various epithelial tumors. Study in mouse suggests that homozygous inactivation of Bin3 causes cataracts and an increased susceptibility to lymphomas during aging.
    Gen-ID
    55909
    NCBI Accession
    NP_061158
    UniProt
    Q9NQY0
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