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BIN3 Antikörper

BIN3 Reaktivität: Human, Maus WB, ELISA Wirt: Maus Monoclonal 3A4 unconjugated
Produktnummer ABIN1043741
  • Target Alle BIN3 Antikörper anzeigen
    BIN3 (Bridging Integrator 3 (BIN3))
    Reaktivität
    • 56
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 46
    • 10
    Maus
    Klonalität
    • 48
    • 8
    Monoklonal
    Konjugat
    • 22
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BIN3 Antikörper ist unkonjugiert
    Applikation
    • 45
    • 22
    • 13
    • 13
    • 7
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    Anti-BIN3 was purified from clarified mouse ascetic fluid by Protein A chromatography followed by extensive dialysis against the buffer stated above. BIN3 antibody is specific for human BIN3 protein. A BLAST analysis was used to suggest cross-reactivity with BIN3 from human and mouse sources based on 100% homology with the immunizing sequence. Cross-reactivity with BIN3 from other sources has not been determined.
    Produktmerkmale
    BIN-3 encodes an evolutionarily conserved and ubiquitously expressed member of the BAR superfamily of curved membrane and GTPase-binding proteins implicated in signal transduction and vesicular trafficking. In humans, Bin3 maps to chromosome 8p21.3, a region widely implicated in cancer suppression that is often deleted in non-Hodgkin’s lymphomas and various epithelial tumors. Study in mouse suggests that homozygous inactivation of Bin3 causes cataracts and an increased susceptibility to lymphomas during aging.
    Sterilität
    Sterile filtered
    Immunogen
    Anti-BIN3 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with a GST tagged full legnth human BIN3 protein followed by hybridoma development.
    Immunogen Type: RecombinantProtein
    Klon
    3A4
    Isotyp
    IgG1
    Top Product
    Discover our top product BIN3 Primärantikörper
  • Applikationshinweise
    Anti-BIN3 antibody has been tested for use in ELISA, Western Blot, and IP. Specific conditions for reactivity should be optimized by the end user.
    Kommentare

    Gene Name: BIN3

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
    Haltbarkeit
    12 months
  • Routhier, Burn, Abbaszade, Summers, Albright, Prendergast: "Human BIN3 complements the F-actin localization defects caused by loss of Hob3p, the fission yeast homolog of Rvs161p." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21670-7, (2001) (PubMed).

  • Target
    BIN3 (Bridging Integrator 3 (BIN3))
    Andere Bezeichnung
    BIN3 (BIN3 Produkte)
    Synonyme
    1700015F07Rik antikoerper, bridging integrator 3 antikoerper, BIN3 antikoerper, Bin3 antikoerper
    Hintergrund
    BIN-3 encodes an evolutionarily conserved and ubiquitously expressed member of the BAR superfamily of curved membrane and GTPase-binding proteins implicated in signal transduction and vesicular trafficking. In humans, Bin3 maps to chromosome 8p21.3, a region widely implicated in cancer suppression that is often deleted in non–Hodgkin’s lymphomas and various epithelial tumors. Study in mouse suggests that homozygous inactivation of Bin3 causes cataracts and an increased susceptibility to lymphomas during aging.
    Synonyms: Bridging integrator 3, BIN-3, BIN 3, BIN3 antibody, anti-BIN3 antibody
    Gen-ID
    55909
    NCBI Accession
    NP_061158
    UniProt
    Q9NQY0
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