IL17F Antikörper (Biotin)
-
- Target Alle IL17F Antikörper anzeigen
- IL17F (Interleukin 17F (IL17F))
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser IL17F Antikörper ist konjugiert mit Biotin
-
Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Hersteller Produkt- Nr.
- 209-306-b31
- Hersteller
- Rockland
- Verwendungszweck
- IL-17F Biotin Conjugated Antibody
- Kreuzreaktivität (Details)
- This antibody is specific for human IL-17F protein.
- Produktmerkmale
- Synonyms: mouse anti-IL-17F biotin conjugated antibody, mouse anti-Interleukin-17F biotin conjugated antibody, Cytokine ML-1, Interleukin-24
- Aufreinigung
- This product was purified from concentrated tissue culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above.
- Immunogen
-
Immunogen: Anti-IL-17F (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17F produced in E.coli followed by hybridoma development.
Immunogen Type: Recombinant Protein
- Klon
- 4H1629-1
- Isotyp
- IgG1
- Labeling Ratio
- 10-20
- Top Product
- Discover our top product IL17F Primärantikörper
-
-
- Applikationshinweise
-
Immunohistochemistry Dilution: 5 μg/mL
Application Note: This purified antibody has been tested for use in IHC and Western Blot. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 0.5 mg/mL
ELISA Dilution: 1:10,000-1:50,000
Other: User Optimized
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
-
Reconstitution Volume: 100 μL
Reconstitution Buffer: Restore with deionized water (or equivalent)
- Konzentration
- 1.0 mg/mL
- Buffer
-
Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
Preservative: 0.01 % (w/v) Sodium Azide - Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store vial at 4° C prior to restoration. Restore with 0.1 mL of deionized water (or equivalent). For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- Haltbarkeit
- 12 months
-
-
Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis." in: The Journal of experimental medicine, Vol. 206, Issue 2, pp. 299-311, (2009) (PubMed).
: "
-
Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis." in: The Journal of experimental medicine, Vol. 206, Issue 2, pp. 299-311, (2009) (PubMed).
-
- Target
- IL17F (Interleukin 17F (IL17F))
- Andere Bezeichnung
- IL17F (IL17F Produkte)
- Hintergrund
- Background: Anti-L-17F recognizes IL-17F (also known as Cytokine ML-1 or Interleukin-24). IL-17F is produced and secreted by CD8+ T cells, NK cells, NKT cells and LTi cells. The main functions of IL-17F are neutrophil recruitment and immunity to extracellular pathogen. More importantly, IL-17F drives inflammation and auto-immunity. IL-17A and IL-17F are by far the best characterized cytokines of the IL-17 cytokine family. IL-17F dimerizes in a parallel fashion similar to nerve growth factor and other neutrophins. Its dimerization is critical to fulfill its activity. When secreted by activated T cells, IL-17F can stimulate the production of other cytokines such as IL-6, IL-8 granulocyte colony-stimulating factor and, can stimulate cartilage matrix turnover. Defects in IL17F are the cause of familial candidiasis type 6 (CANDF6). CANDF6 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. Anti-IL-17E cytokine antibody is ideal for investigators involved in Immunology, Signal Transduction research, Cancer and Inflammatory pathologies.
- Gen-ID
- 112744
- NCBI Accession
- NP_443104
- UniProt
- Q96PD4
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
-