NFYA Antikörper (N-Term)

Produktnummer ABIN104769

Produktdetails anti-NFYA Antikörper

Target: NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFYA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktmerkmale: Concentration Definition: by UV absorbance at 280 nm

Immunogen: Anti-NF-Y (A) antibody was produced by repeated immunizations with a synthetic NF-Y (A subunit) peptide corresponding to a region near the of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Anti-NF-Y antibody is suitable for western blotting and for ELISA. Researchers should determine optimal titers for applications that are not stated below.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-NFYA Antikörper (ABIN104769)

Falcone, Grandoni, Garibaldi, Manni, Filligoi, Piaggio, Gurtner: "Infinity: An In-Silico Tool for Genome-Wide Prediction of Specific DNA Matrices in miRNA Genomic Loci." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153658, (2016) (PubMed).

Gurtner, Fuschi, Magi, Colussi, Gaetano, Dobbelstein, Sacchi, Piaggio: "NF-Y dependent epigenetic modifications discriminate between proliferating and postmitotic tissue." in: PLoS ONE, Vol. 3, Issue 4, pp. e2047, (2008) (PubMed).

Cecchinelli, Lavra, Rinaldo, Iacovelli, Gurtner, Gasbarri, Ulivieri, Del Prete, Trovato, Piaggio, Bartolazzi, Soddu, Sciacchitano: "Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis." in: Molecular and cellular biology, Vol. 26, Issue 12, pp. 4746-57, (2006) (PubMed).

Yu, Zhu, Pi, Ling, Ko, Takeda, Tuan: "The long terminal repeat (LTR) of ERV-9 human endogenous retrovirus binds to NF-Y in the assembly of an active LTR enhancer complex NF-Y/MZF1/GATA-2." in: The Journal of biological chemistry, Vol. 280, Issue 42, pp. 35184-94, (2005) (PubMed).

Details zu NFYA

Target: NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

Abstract: NFYA Produkte

Synonyme: wu:fb16e03 antikoerper, ik:tdsubc_2b6 antikoerper, xx:tdsubc_2b6 antikoerper, NFYA antikoerper, CBF-A antikoerper, CBF-B antikoerper, HAP2 antikoerper, NF-YA antikoerper, AA407810 antikoerper, Cbf-b antikoerper, SEZ-10 antikoerper, SEZ10 antikoerper, nuclear transcription factor Y, alpha antikoerper, nuclear transcription factor Y subunit alpha antikoerper, nuclear transcription factor-Y alpha antikoerper, nfya antikoerper, NFYA antikoerper, Nfya antikoerper

Hintergrund: Anti-NF-Y antibody detects NF-Y (a subunit) protein. NF-Y is a highly conserved transcription factor that stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes. NF-subunit A associates with a tight dimer composed of the NF-YB and NF-YC subunits, resulting in a trimer that binds to DNA with high specificity and affinity. Anti-NF-YA Antibody is ideal for investigators involved in Cell Signaling, Immunology, Cancer, and Signal Transduction research.
Synonyms: Nf-Y-A subunit, CAAT box DNA-binding protein subunit A, Nuclear transcription factor Y subunit A

Gen-ID: 4800

UniProt: P23511

Pathways: Regulation of Lipid Metabolism by PPARalpha