PPARD Antikörper

Produktnummer ABIN105799

Produktdetails anti-PPARD Antikörper

Target: PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPARD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktmerkmale: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the amino terminus of mouse PPAR delta.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a single band approximately 43 kDa in size corresponding to PPAR delta by western blot in the appropriate tissue or cell lysate.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.57 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-PPARD Antikörper (ABIN105799)

Matsushita, Hassanein, Martinez-Clemente, Lazaro, French, Xie, Lai, Karin, Tsukamoto: "Gender difference in NASH susceptibility: Roles of hepatocyte Ikkβ and Sult1e1." in: PLoS ONE, Vol. 12, Issue 8, pp. e0181052, (2017) (PubMed).

Details zu PPARD

Target: PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

Andere Bezeichnung: PPAR Delta (PPARD Produkte)

Synonyme: FAAR antikoerper, NR1C2 antikoerper, NUC1 antikoerper, NUCI antikoerper, NUCII antikoerper, PPARB antikoerper, NUC-1 antikoerper, Nr1c2 antikoerper, PPAR-beta antikoerper, PPAR-delta antikoerper, PPAR[b] antikoerper, PPARdelta antikoerper, Pparb antikoerper, Pparb/d antikoerper, PPARBETA antikoerper, ppard antikoerper, pparb antikoerper, PPARD antikoerper, PPAR-D/B antikoerper, peroxisome proliferator activated receptor delta antikoerper, peroxisome proliferator activator receptor delta antikoerper, peroxisome proliferator activated receptor delta S homeolog antikoerper, peroxisome proliferator-activated receptor delta antikoerper, PPARD antikoerper, Ppard antikoerper, ppard.S antikoerper, ppard antikoerper

Hintergrund: Since their discovery in the early 1990's, the peroxisome proliferator activated receptors (PPARs) have attracted significant attention. This is primarily because PPARs serve as receptors for two very important classes of drugs: the hypolipidemic fibrates and the insulin sensitizing thiazolidinediones.  Peroxisome proliferators are non-genotoxic carcinogens that are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed PPARs. Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Upon binding fatty acids or hypolipidemic drugs, PPARs
Synonyms: MGC3931 antibody, NR1C2 antibody, NUC1 antibody, NUCI antibody, NUCII antibody, Nuclear hormone receptor 1 antibody, Nuclear receptor subfamily 1 group C member 2 antibody, Peroxisome proliferative activated receptor delta antibod

Gen-ID: 19015, 548577

UniProt: P35396

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation