PANX1 Antikörper (N-Term)
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- Target Alle PANX1 Antikörper anzeigen
- PANX1 (Pannexin 1 (PANX1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PANX1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Spezifität
- Two transcript variants encoding different isoforms have been found for this gene.
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- Rabbit polyclonal PANX1 antibody was raised against a 17 amino acid peptide near the amino terminus of human PANX1.
- Isotyp
- IgG
- Top Product
- Discover our top product PANX1 Primärantikörper
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- Applikationshinweise
- PANX1 antibody can be used for detection of PANX1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
- Kommentare
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(NT) Pannexin 1
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- PANX1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Haltbarkeit
- 12 months
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- Target
- PANX1 (Pannexin 1 (PANX1))
- Andere Bezeichnung
- PANX1 (PANX1 Produkte)
- Synonyme
- panx1 antikoerper, zgc:55631 antikoerper, PANX1 antikoerper, px1 antikoerper, mrs1 antikoerper, pannexin1 antikoerper, Pannexin-1 antikoerper, MRS1 antikoerper, PX1 antikoerper, UNQ2529 antikoerper, AI847747 antikoerper, pannexin 1a antikoerper, pannexin 1 antikoerper, Pannexin 1 antikoerper, panx1a antikoerper, PANX1 antikoerper, panx1 antikoerper, Panx1 antikoerper
- Hintergrund
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The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
Synonyms: Pannexin 1, Pannexin-1, PX1, MRS1, UNQ2529, UNQ2529/PRO6028 - Molekulargewicht
- 47 kDa
- Gen-ID
- 24145
- NCBI Accession
- NP_056183
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