CHCHD6 Antikörper (N-Term)
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- Target Alle CHCHD6 Antikörper anzeigen
- CHCHD6 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6 (CHCHD6))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CHCHD6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- CHCHD6 is predicted to not cross-react to other members of the CHCHD family.
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- Rabbit polyclonal CHCHD6 antibody was raised against a 17 amino acid peptide near the amino terminus of human CHCHD6.
- Isotyp
- IgG
- Top Product
- Discover our top product CHCHD6 Primärantikörper
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- Applikationshinweise
- CHCHD6 antibody can be used for detection of CHCHD6 by Western blot at 1 - 2 μg/mL.
- Kommentare
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(NT) Coiled-coil-helix-coiled-coil-helix domain-containing protein 6
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- CHCHD6 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Haltbarkeit
- 12 months
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- Target
- CHCHD6 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6 (CHCHD6))
- Andere Bezeichnung
- CHCHD6 (CHCHD6 Produkte)
- Synonyme
- CHCM1 antikoerper, PPP1R23 antikoerper, 0710001P09Rik antikoerper, 1700021B03Rik antikoerper, chchd6 antikoerper, hm:zeh0124 antikoerper, zgc:91802 antikoerper, coiled-coil-helix-coiled-coil-helix domain containing 6 antikoerper, coiled-coil-helix-coiled-coil-helix domain containing 6a antikoerper, CHCHD6 antikoerper, Chchd6 antikoerper, chchd6a antikoerper
- Hintergrund
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CHCHD6 is a member of a family of proteins containing a conserved (coiled coil 1)-(helix 1)-(coiled coil 2)-(helix 2) domain and has been observed in a complex with the mitochondrial proteins mitofilin, SAM50, metaxins 1 and 2, and CHCHD3. CHCHD6 knockdown causes severe defects in mitochondrial cristae morphology as well as reductions in cell growth, ATP production and oxygen consumption. This decrease of CHCHD6 also led to a reduction in mitofilin protein levels, while a knockdown of mitofilin resulted in a reduced level of CHCHD6, suggesting coordinate regulation between these two proteins. CHCHD6 knockdown in human cancer cells enhances their sensitivity to genotoxic anticancer drugs, suggesting that CHCHD6 may be a potential therapeutic anti-tumor target.
Synonyms: Coiled-coil-helix-coiled-coil-helix domain-containing protein 6, coiled coil helix cristae morphology 1, CHCM1, PPP1R23 - Molekulargewicht
- 26 kDa (calculated)
- Gen-ID
- 84303
- NCBI Accession
- NP_115719
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