TYK2 Antikörper (N-Term)
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- Target Alle TYK2 Antikörper anzeigen
- TYK2 (Tyrosine Kinase 2 (TYK2))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TYK2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- At least three isoforms of TYK2 are known to exist, this antibody only detects the two longest isoforms.
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- Rabbit polyclonal TYK2 antibody was raised against a 17 amino acid peptide near the amino terminus of human TYK2.
- Isotyp
- IgG
- Top Product
- Discover our top product TYK2 Primärantikörper
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- Applikationshinweise
- TYK2 antibody can be used for detection of TYK2 by Western blot at 1 - 2 μg/mL.
- Kommentare
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(NT) Tyrosine kinase 2
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- TYK2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Haltbarkeit
- 12 months
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- Target
- TYK2 (Tyrosine Kinase 2 (TYK2))
- Andere Bezeichnung
- TYK2 (TYK2 Produkte)
- Synonyme
- JTK1 antikoerper, tyrosine kinase 2 antikoerper, TYK2 antikoerper, Tyk2 antikoerper
- Hintergrund
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TYK2 is a member of the Janus kinases (JAKs) protein families. TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits and is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
Synonyms: Tyrosine kinase 2, non-receptor tyrosine kinase 2 - Molekulargewicht
- 131 kDa (calculated)
- Gen-ID
- 7297
- NCBI Accession
- NP_003322
- Pathways
- JAK-STAT Signalweg, Hepatitis C
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