BCL3 Antikörper (C-Term)
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- Target Alle BCL3 Antikörper anzeigen
- BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BCL3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- Rabbit polyclonal BCL3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human BCL3.
- Isotyp
- IgG
- Top Product
- Discover our top product BCL3 Primärantikörper
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- Applikationshinweise
- BCL3 antibody can be used for detection of BCL3 by Western blot at 1 - 2 μg/mL.
- Kommentare
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(CT) B-cell CLL/lymphoma 3
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- BCL3 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Haltbarkeit
- 12 months
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- Target
- BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
- Andere Bezeichnung
- BCL3 (BCL3 Produkte)
- Synonyme
- BCL3 antikoerper, AI528691 antikoerper, Bcl-3 antikoerper, BCL4 antikoerper, D19S37 antikoerper, B-cell CLL/lymphoma 3 antikoerper, B cell leukemia/lymphoma 3 antikoerper, BCL3 antikoerper, Bcl3 antikoerper
- Hintergrund
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The proto-oncogene Bcl-3, believed to be involved in certain human B cell leukemias, encodes a protein that contributes to the regulation of transcriptional activation of NF-k-B target genes. BCL3 contains seven ankyrin repeats, which are most closely related to those found in I-k-B proteins. The expression of this gene can be induced by NF-k-B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-k-B. It contributes to the regulation of cell proliferation. A chromosomal aberration involving BCL3 may be a cause of B-cell chronic lymphocytic leukemia.
Synonyms: B-cell CLL/lymphoma 3, BCL-3, BCL4, D19S37, Proto-oncogene BCL3 - Molekulargewicht
- 50 kDa (calculated)
- Gen-ID
- 602
- NCBI Accession
- NP_005169
- Pathways
- NF-kappaB Signalweg, Maintenance of Protein Location, Protein targeting to Nucleus
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