KREMEN1 Antikörper (C-Term)
-
- Target Alle KREMEN1 Antikörper anzeigen
- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
-
Bindungsspezifität
- C-Term
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser KREMEN1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA
- Spezifität
- Three isoforms of KREMEN1 exists as a result of alternative splicing event.
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- Rabbit polyclonal KREMEN1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KREMEN1.
- Isotyp
- IgG
- Top Product
- Discover our top product KREMEN1 Primärantikörper
-
-
- Applikationshinweise
- KREMEN1 antibody can be used for detection of KREMEN1 by Western blot at 0.5 - 1 μg/mL.
- Kommentare
-
(CT) Kringle-containing protein marking the eye and the nose
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Lagerung
- 4 °C/-20 °C
-
- Target
- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
- Andere Bezeichnung
- KREMEN1 (KREMEN1 Produkte)
- Synonyme
- KREMEN1 antikoerper, krm1 antikoerper, kremen antikoerper, kremem1 antikoerper, KREMEN antikoerper, KRM1 antikoerper, AV002070 antikoerper, Kremen antikoerper, Krm1 antikoerper, si:ct737139.1 antikoerper, si:dkeyp-7c9.1 antikoerper, kringle containing transmembrane protein 1 antikoerper, kringle containing transmembrane protein 1 S homeolog antikoerper, KREMEN1 antikoerper, kremen1 antikoerper, Kremen1 antikoerper, kremen1.S antikoerper
- Hintergrund
-
Kremen (Kringle containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Kremens bind a subset of the secreted Dickkopf proteins (Dkk 1, 2, and 4) with high affinity to modulate the canonical Wnt signaling pathway that is transduced by the ternary receptor complex composed of Wnt, Frizzled, and the LDL receptor related protein 5/6 (LRP5/6) coreceptor. KREMEN1 is a receptor for the Dickkopf protein which blocks Wnt/beta catenin signaling. It is necessary to ensure normal spatial and temporal patterns of Wnt activity during developmental processes.
Synonyms: Kringle-containing protein marking the eye and the nose, Kringle containing transmembrane protein 1, KRM1, Dickkopf receptor - Molekulargewicht
- 54 kDa
- Gen-ID
- 83999
- NCBI Accession
- NP_114434
- Pathways
- WNT Signalweg
-