SDPR Antikörper (N-Term)
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- Target Alle SDPR Antikörper anzeigen
- SDPR (Serum Deprivation Response (SDPR))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SDPR Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- It is predicted to not cross-react with other members of the cavin family.
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- Rabbit polyclonal SDPR antibody was raised against an 18 amino acid peptide near the amino terminus of human SDPR.
- Isotyp
- IgG
- Top Product
- Discover our top product SDPR Primärantikörper
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- Applikationshinweise
- SDPR antibody can be used for detection of SDPR by Western blot at 1 - 2 μg/mL.
- Kommentare
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(NT) Serum deprivation-response protein
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Lagerung
- 4 °C/-20 °C
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- Target
- SDPR (Serum Deprivation Response (SDPR))
- Andere Bezeichnung
- SDPR (SDPR Produkte)
- Synonyme
- CAVIN2 antikoerper, PS-p68 antikoerper, SDR antikoerper, cavin-2 antikoerper, sdr antikoerper, MGC84112 antikoerper, sdprb antikoerper, wu:fb39c08 antikoerper, wu:fk90b02 antikoerper, zgc:92231 antikoerper, caveolae associated protein 2 antikoerper, caveolae associated 2 antikoerper, caveolae associated protein 2 S homeolog antikoerper, serum deprivation response antikoerper, caveolae associated protein 2b antikoerper, CAVIN2 antikoerper, Cavin2 antikoerper, cavin2.S antikoerper, SDPR antikoerper, cavin2b antikoerper
- Hintergrund
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The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP were down regulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.
Synonyms: Serum deprivation response, SDR, serum deprivation-response protein, CAVIN2, PS-p68, cavin-2, phosphatidylserine binding protein - Molekulargewicht
- 47 kDa
- Gen-ID
- 8436
- NCBI Accession
- NP_004648
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