HSP90 Antikörper

Produktnummer ABIN108447

Produktdetails anti-HSP90 Antikörper

Target: HSP90 (Heat Shock Protein 90 (HSP90))

Reaktivität: Human, Salmon

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSP90 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität (Details): Not reactive in: no confirmed exceptions from predicted reactivity known in the moment

Homologie: fishes, hen, mammals

Produktmerkmale: Expected / apparent Molecular Weight of the Antigene: 84-86 kDa
Antibody has been used on extracts from bovine brain, thymus, muscle, lung,heart, liver, kidney and spleen .

Aufreinigung: serum

Immunogen: KLH-conjugated synthetic peptide chosen from a highly conserved region of hsp90 found in both the alpha P07900 and beta P08238 form of the protein. The target peptide is perfectly conserved in animals.

Anwendungsinformationen

Applikationshinweise: 1: 5 000 with standard ECL (WB)

Kommentare:

in salmonid fish a cross-reactive band at approximately 40 kDa is observed, antibody will also detect a human recombinant HSP90 protein

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: For reconstitution add 100 μL of sterile water

Handhabung: Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
Once reconstituted make aliquots to avoid repreated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

Referenzen für anti-HSP90 Antikörper (ABIN108447)

Rendell, Fowler, Cockshutt, Currie: "Development-dependent differences in intracellular localization of stress proteins (hsps) in rainbow trout, Oncorhynchus mykiss, following heat shock." in: Comparative biochemistry and physiology. Part D, Genomics & proteomics, Vol. 1, Issue 2, pp. 238-52, (2010) (PubMed).

Details zu HSP90

Target: HSP90 (Heat Shock Protein 90 (HSP90))

Andere Bezeichnung: HSP90 (HSP90 Produkte)

Hintergrund: HSP90 is a ubiquitous chaperone involved in numerous cellular processes. Members of this family of proteins play important roles in allowing a selected group of intracellular signaling molecules reach and maintain functionally active conformations.Alternative names: for hsp90 alpha: HSP 86, renal carcinoma antigen NY-REN-38, for hsp90 beta: hsp84

Molekulargewicht: 84-86 kDa

UniProt: P07900, P08238

Pathways: M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals