THO Complex 4 Antikörper

Produktnummer ABIN108543

Produktdetails anti-THO Complex 4 Antikörper

Target: THO Complex 4 (THOC4)

Reaktivität: Human, Maus, Xenopus laevis

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser THO Complex 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP), Electron Microscopy (EM), Flow Cytometry (FACS)

Aufreinigung: Protein A

Immunogen: Recombinant human ALY / REF fusion protein

Klon: 11G5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal antibody dilution should be determined by titration, however as a guideline try: IHC-P: Use a concentration of 1 μg/mL. ICC/IF: 1/50. PubMed: 17103222 WB: 1/1500. Detects a band of approximately 32 kDa (predicted molecular weight: 27 kDa).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-THO Complex 4 Antikörper (ABIN108543)

Ding, Enriquez-Algeciras, Dave, Perez-Pinzon, Bhattacharya: "The role of deimination in ATP5b mRNA transport in a transgenic mouse model of multiple sclerosis." in: EMBO reports, Vol. 13, Issue 3, pp. 230-6, (2012) (PubMed).

Domínguez-Sánchez, Sáez, Japón, Aguilera, Luna: "Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers." in: BMC cancer, Vol. 11, pp. 77, (2011) (PubMed).

Thomas, Lischka, Müller, Stamminger: "The cellular DExD/H-box RNA-helicases UAP56 and URH49 exhibit a CRM1-independent nucleocytoplasmic shuttling activity." in: PLoS ONE, Vol. 6, Issue 7, pp. e22671, (2011) (PubMed).

Read, Digard: "Individual influenza A virus mRNAs show differential dependence on cellular NXF1/TAP for their nuclear export." in: The Journal of general virology, Vol. 91, Issue Pt 5, pp. 1290-301, (2010) (PubMed).

Katahira, Inoue, Hurt, Yoneda: "Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA." in: The EMBO journal, Vol. 28, Issue 5, pp. 556-67, (2009) (PubMed).

Nojima, Hirose, Kimura, Hagiwara: "The interaction between cap-binding complex and RNA export factor is required for intronless mRNA export." in: The Journal of biological chemistry, Vol. 282, Issue 21, pp. 15645-51, (2007) (PubMed).

van Koningsbruggen, Straasheijm, Sterrenburg, de Graaf, Dauwerse, Frants, van der Maarel: "FRG1P-mediated aggregation of proteins involved in pre-mRNA processing." in: Chromosoma, Vol. 116, Issue 1, pp. 53-64, (2007) (PubMed).

Kim, Yong, Kataoka, Abel, Diem, Dreyfuss: "The Y14 protein communicates to the cytoplasm the position of exon-exon junctions." in: The EMBO journal, Vol. 20, Issue 8, pp. 2062-8, (2001) (PubMed).

Details zu THO Complex 4

Target: THO Complex 4 (THOC4)

Andere Bezeichnung: ALY (THOC4 Produkte)

Synonyme: THOC4 antikoerper, Aly antikoerper, ALY antikoerper, ALY/REF antikoerper, BEF antikoerper, REF antikoerper, tho4 antikoerper, thoc4 antikoerper, zgc:171753 antikoerper, Tho4-A antikoerper, alyref-a antikoerper, thoc4-a antikoerper, REF1 antikoerper, Refbp1 antikoerper, Thoc4 antikoerper, Tho4 antikoerper, Aly/REF export factor antikoerper, THO complex 4 antikoerper, Aly/REF export factor L homeolog antikoerper, ALYREF antikoerper, Thoc4 antikoerper, alyref antikoerper, alyref.L antikoerper, Alyref antikoerper

Hintergrund: Synonyms:
Ally of AML1 and LEF1 antibody,BEF antibody,bZIP enhancing factor antibody,REF antibody,THO complex 4antibody,THOC 4 antibody,THOC-4 antibody,THOC4 antibody,Transcriptional coactivatorantibody

Gen-ID: 10189, 21681

OMIM: 604171

UniProt: O08583