FMR1 Antikörper (C-Term)

Produktnummer ABIN108598

Produktdetails anti-FMR1 Antikörper

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Bindungsspezifität: C-Term

Reaktivität: Drosophila melanogaster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FMR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Keine Kreuzreaktivität: Human

Kreuzreaktivität (Details): Fruit fly (Drosophila melanogaster) Does not react with Human

Aufreinigung: Protein A

Immunogen: His-dFMR1 fusion protein (Drosophilia melanogaster) (C-terminal 580aa).

Klon: 6A15

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal antibody dilution should be determined by titration, however as a guideline try at IP: Use at 25 μg/mg of lysate WB: Use at an assay dependent dilution. Detects a band of approximately 85 kDa (predicted molecular weight: 82 kDa)

Kommentare:

Myeloma, fusion partners: SP2/0

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-FMR1 Antikörper (ABIN108598)

Callan, Clements, Ahrendt, Zarnescu: "Fragile X Protein is required for inhibition of insulin signaling and regulates glial-dependent neuroblast reactivation in the developing brain." in: Brain research, Vol. 1462, pp. 151-61, (2012) (PubMed).

Lim, Lee, Choi, Kilman, Kim, Park, Jang, Allada, Choe: "The novel gene twenty-four defines a critical translational step in the Drosophila clock." in: Nature, Vol. 470, Issue 7334, pp. 399-403, (2011) (PubMed).

Monzo, Dowd, Minden, Sisson: "Proteomic analysis reveals CCT is a target of Fragile X mental retardation protein regulation in Drosophila." in: Developmental biology, Vol. 340, Issue 2, pp. 408-18, (2010) (PubMed).

Callan, Cabernard, Heck, Luois, Doe, Zarnescu: "Fragile X protein controls neural stem cell proliferation in the Drosophila brain." in: Human molecular genetics, Vol. 19, Issue 15, pp. 3068-79, (2010) (PubMed).

Kwak, Drier, Barbee, Ramaswami, Yin, Wickens: "GLD2 poly(A) polymerase is required for long-term memory." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 38, pp. 14644-9, (2008) (PubMed).

Monzo, Papoulas, Cantin, Wang, Yates, Sisson: "Fragile X mental retardation protein controls trailer hitch expression and cleavage furrow formation in Drosophila embryos." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 48, pp. 18160-5, (2006) (PubMed).

Wan, Dockendorff, Jongens, Dreyfuss: "Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein." in: Molecular and cellular biology, Vol. 20, Issue 22, pp. 8536-47, (2000) (PubMed).

Details zu FMR1

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Andere Bezeichnung: Drosophila FMR1 (FMR1 Produkte)

Synonyme: AT24755 antikoerper, BcDNA:GM08679 antikoerper, CG6203 antikoerper, Dmel\\CG6203 antikoerper, EP(3)3517 antikoerper, FMR antikoerper, FMR1 antikoerper, FMRP antikoerper, FMRp antikoerper, FXR antikoerper, Fmrp antikoerper, cg6203 antikoerper, dFMR antikoerper, dFMR1 antikoerper, dFMRP antikoerper, dFXR antikoerper, dFXR1 antikoerper, dFXRP antikoerper, dFmr1 antikoerper, dFmrp antikoerper, dfmr antikoerper, dfmr1 antikoerper, dfxr antikoerper, dfxr1 antikoerper, dmfr1 antikoerper, fmr antikoerper, fmr1 antikoerper, FRAXA antikoerper, POF antikoerper, POF1 antikoerper, zFMR1 antikoerper, Fmr-1 antikoerper, CG6203 gene product from transcript CG6203-RC antikoerper, fragile X mental retardation 1 antikoerper, fragile X mental retardation syndrome 1 antikoerper, Fmr1 antikoerper, FMR1 antikoerper, fmr1 antikoerper

Hintergrund: Synonyms:
Drosophila FMR1 antibody,dFMR antibody,dFMR1 antibody,dFXR antibody,Drosophila fragile X mentalretardation protein antibody,FMRP antibody,Fragile X mental retardation 1 antibody,Fragile X mental retardation1 protein antibody,fragile X mental retardation protein antibody,FRAXA antibody,Protein FMR1antibody

Gen-ID: 37528, 23879

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development