CEACAM1 Antikörper

Produktnummer ABIN108725

Produktdetails anti-CEACAM1 Antikörper

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CEACAM1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Cell-ELISA (cELISA)

Spezifität: GM8G5 recognises CEACAM1 transiently expressed on the cell surface of transfected BOSC cells as well as the naturally expressed protein (Fig. 2, kindly provided by Dr. R. Riesenberg, Labor für Tumorimmunologie, Urologische Klinik, Klinikum Grossh

Aufreinigung: Protein G

Immunogen: genetic immunisation with cDNA encoding the extracellular region of human CEACAM1-A2

Klon: GM-8G5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
ELISA: 1:200 - 1:400
Immunohistology: 10 µg/mL (on cryosections)
For each application a titration should be performed to determine the optimal concentration.

Kommentare:

Synonyms: CD66a, BGP, biliary glycoprotein I

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.2

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C

Informationen zur Lagerung: short term: 2 °C - 8 °C, long term: -20 °C

Details zu CEACAM1

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Andere Bezeichnung: CEACAM1 (CEACAM1 Produkte)

Hintergrund: CEACAM1 (BGP) belongs to the carcinoembryonic antigen (CEA) gene family. CEACAM1 expression is downregulated in many tumors indicating a tumor-suppressive function. GM8G5 was generated by genetic immunisation and can be used to distinguish CEACAM1 from all other CEACAMs.

UniProt: P13688