SRY Antikörper (AA 1-204)

Produktnummer ABIN1098106

Produktdetails anti-SRY Antikörper

Target: SRY (Sex Determining Region Y (SRY))

Bindungsspezifität: AA 1-204

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SRY Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human SRY (AA:1-204) expressed in E. coli.

Klon: 1G4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-SRY Antikörper (ABIN1098106)

Peng, Ivanov, Oh, Lau, Rauscher: "Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery." in: The Journal of biological chemistry, Vol. 284, Issue 51, pp. 35670-80, (2009) (PubMed).

Wu, Chen, Li, Lau, Shih: "Regulation of monoamine oxidase A by the SRY gene on the Y chromosome." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 11, pp. 4029-38, (2009) (PubMed).

Details zu SRY

Target: SRY (Sex Determining Region Y (SRY))

Andere Bezeichnung: SRY (SRY Produkte)

Synonyme: SRXX1 antikoerper, SRXY1 antikoerper, TDF antikoerper, TDY antikoerper, SRYGENE antikoerper, Sry1 antikoerper, Sry3BI antikoerper, Tdf antikoerper, Tdy antikoerper, SRY antikoerper, sex determining region Y antikoerper, sex determining region of Chr Y antikoerper, SRY antikoerper, Sry antikoerper

Hintergrund:

Description: This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome), translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.

Aliases: TDF, TDY, SRXX1, SRXY1

Molekulargewicht: 23.9 kDa

Gen-ID: 6736

HGNC: 6736