RAG1 Antikörper (AA 818-868)

Produktnummer ABIN1098121

Produktdetails anti-RAG1 Antikörper

Target: RAG1 (Recombination Activating Gene 1 (RAG1))

Bindungsspezifität: AA 818-868

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RAG1 Antikörper ist unkonjugiert

Applikation: ELISA

Verwendungszweck: RAG1 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human RAG1 (AA: 818-868) expressed in E. Coli.

Klon: 1D9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-RAG1 Antikörper (ABIN1098121)

Chen, Xiao, Zhang, Li, Liu, Zhao, Ma, Luo, Qiu, Huang, Korteweg, Gu: "Transcription factors E2A, FOXO1 and FOXP1 regulate recombination activating gene expression in cancer cells." in: PLoS ONE, Vol. 6, Issue 5, pp. e20475, (2011) (PubMed).

Jones, Bhattacharyya, Simkus, Vallieres, Veenstra, Zhou: "The RAG1 V(D)J recombinase/ubiquitin ligase promotes ubiquitylation of acetylated, phosphorylated histone 3.3." in: Immunology letters, Vol. 136, Issue 2, pp. 156-62, (2011) (PubMed).

Details zu RAG1

Target: RAG1 (Recombination Activating Gene 1 (RAG1))

Andere Bezeichnung: RAG1 (RAG1 Produkte)

Synonyme: RAG-1 antikoerper, rag1 antikoerper, RNF74 antikoerper, Rag-1 antikoerper, rag-1 antikoerper, rag1a antikoerper, recombination activating 1 antikoerper, recombination activating gene 1 antikoerper, recombination activating gene 1 S homeolog antikoerper, Rag1 antikoerper, RAG1 antikoerper, rag1 antikoerper, rag1.S antikoerper

Hintergrund:

Description: The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases.

Aliases: RAG-1, RNF74, MGC43321

Molekulargewicht: 119kDa

Gen-ID: 5896

HGNC: 5896

UniProt: P15918