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NEFH Antikörper (AA 968-1020)

Name: NEFH Antikörper (AA 968-1020)
Brand: antibodies-online
SKU: ABIN1098127
Price: 640.59 EUR
Availability: InStock

NEFH Reaktivität: Human IHC, ELISA Wirt: Maus Monoclonal 8H10 unconjugated

Immunohistochemical analysis of paraffin-embedded medulla oblongata tissues using NEFH mouse mAb with DAB staining. (NEFH Antikörper (AA 968-1020))

IHC

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (NEFH Antikörper (AA 968-1020))

ELISA

Western blot analysis using NEFH mAb against human NEFH recombinant protein. (NEFH Antikörper (AA 968-1020))

Western blot analysis using NEFH mAb against HEK293 (1) and NEFH (AA: 968-1020)-hIgGFc transfected HEK293 (2) cell lysate. (NEFH Antikörper (AA 968-1020))

4 Abbildungen

(2 Referenzen)

Produktnummer ABIN1098127

Datenblatt (PDF)

Target Alle NEFH Antikörper anzeigen

NEFH (Neurofilament, Heavy Polypeptide (NEFH))
Bindungsspezifität
16

8

4

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 968-1020
Reaktivität
113

83

64

50

31

23

12

12

9

9

9

7

7

5

3

3

2

2

1

1
Human
Wirt
67

57

8
Maus
Passende Sekundärantikörper
Klonalität
82

50
Monoklonal
Konjugat
83

5

3

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser NEFH Antikörper ist unkonjugiert
Applikation
82

40

37

26

25

24

20

14

13

13

12

9

5

2

2

2

2

2

1

1

1
Immunohistochemistry (IHC), ELISA

Verwendungszweck

NEFH Antibody

Aufreinigung

Purified antibody

Immunogen

Purified recombinant fragment of human NEFH (AA: 968-1020) expressed in E. Coli.

Klon

8H10

Isotyp

IgG1

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Applikationshinweise

ELISA: 1/10000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Singh, Yan, Hull, Read, OSullivan, Henderson, Rose, Greer, McCombe: "Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke." in: Journal of the neurological sciences, Vol. 304, Issue 1-2, pp. 117-21, (2011) (PubMed).

Sellner, Patel, Dassan, Brown, Petzold: "Hyperacute detection of neurofilament heavy chain in serum following stroke: a transient sign." in: Neurochemical research, Vol. 36, Issue 12, pp. 2287-91, (2011) (PubMed).
Target

NEFH (Neurofilament, Heavy Polypeptide (NEFH))

Andere Bezeichnung

NEFH (NEFH Produkte)

Synonyme

NF-H antikoerper, NF200 antikoerper, Nfh antikoerper, mKIAA0845 antikoerper, NFH antikoerper, NEFH antikoerper, neurofilament heavy polypeptide antikoerper, neurofilament, heavy polypeptide antikoerper, neurofilament heavy antikoerper, MCYG_06231 antikoerper, Nefh antikoerper, NEFH antikoerper

Hintergrund

Description: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.

Aliases: NFH

Molekulargewicht

112.4kDa

Gen-ID

4744

HGNC

4744

UniProt

P12036