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LMO2 Antikörper (AA 1-158)

LMO2 Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 4D8 unconjugated
Produktnummer ABIN1098128
  • Target Alle LMO2 Antikörper anzeigen
    LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))
    Bindungsspezifität
    • 14
    • 9
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-158
    Reaktivität
    • 43
    • 11
    • 8
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 34
    • 7
    • 3
    Maus
    Klonalität
    • 34
    • 10
    Monoklonal
    Konjugat
    • 30
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser LMO2 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 23
    • 20
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    ELISA, Flow Cytometry (FACS)
    Verwendungszweck
    LMO2 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human LMO2 (AA: 1-158) expressed in E. Coli.
    Klon
    4D8
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Cubedo, Maurin, Jiang, Lossos, Wright: "PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL." in: The FEBS journal, Vol. 278, Issue 17, pp. 3065-75, (2011) (PubMed).

    Baecklund, Backlin, Mansouri, Klareskog, Askling, Iliadou, Enblad, Lossos, Natkunam, Rosenquist: "LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma." in: Leukemia & lymphoma, Vol. 52, Issue 6, pp. 1146-9, (2011) (PubMed).

  • Target
    LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))
    Andere Bezeichnung
    LMO2 (LMO2 Produkte)
    Synonyme
    Rbtn-2 antikoerper, Rbtn2 antikoerper, Rhom-2 antikoerper, Ttg2 antikoerper, RBTN2 antikoerper, RBTNL1 antikoerper, RHOM2 antikoerper, TTG2 antikoerper, wu:fc83a08 antikoerper, zgc:111930 antikoerper, LMO-2 antikoerper, lmo2-A antikoerper, xlmo2 antikoerper, rhombotin-2 antikoerper, LIM domain only 2 antikoerper, LIM domain only 2 (rhombotin-like 1) antikoerper, LIM domain only 2 S homeolog antikoerper, lmo2 antikoerper, LMO2 antikoerper, Lmo2 antikoerper, lmo2.S antikoerper
    Hintergrund

    Description: LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Aliases: TTG2, RBTN2, RHOM2, RBTNL1

    Molekulargewicht
    18.4kDa
    Gen-ID
    4005
    HGNC
    4005
    UniProt
    P25791
    Pathways
    Chromatin Binding
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