LMO2 Antikörper (AA 1-158)
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- Target Alle LMO2 Antikörper anzeigen
- LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))
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Bindungsspezifität
- AA 1-158
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser LMO2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Flow Cytometry (FACS)
- Verwendungszweck
- LMO2 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human LMO2 (AA: 1-158) expressed in E. Coli.
- Klon
- 4D8
- Isotyp
- IgG1
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL." in: The FEBS journal, Vol. 278, Issue 17, pp. 3065-75, (2011) (PubMed).
: "LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma." in: Leukemia & lymphoma, Vol. 52, Issue 6, pp. 1146-9, (2011) (PubMed).
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PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL." in: The FEBS journal, Vol. 278, Issue 17, pp. 3065-75, (2011) (PubMed).
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- Target
- LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))
- Andere Bezeichnung
- LMO2 (LMO2 Produkte)
- Synonyme
- Rbtn-2 antikoerper, Rbtn2 antikoerper, Rhom-2 antikoerper, Ttg2 antikoerper, RBTN2 antikoerper, RBTNL1 antikoerper, RHOM2 antikoerper, TTG2 antikoerper, wu:fc83a08 antikoerper, zgc:111930 antikoerper, LMO-2 antikoerper, lmo2-A antikoerper, xlmo2 antikoerper, rhombotin-2 antikoerper, LIM domain only 2 antikoerper, LIM domain only 2 (rhombotin-like 1) antikoerper, LIM domain only 2 S homeolog antikoerper, lmo2 antikoerper, LMO2 antikoerper, Lmo2 antikoerper, lmo2.S antikoerper
- Hintergrund
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Description: LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.
Aliases: TTG2, RBTN2, RHOM2, RBTNL1
- Molekulargewicht
- 18.4kDa
- Gen-ID
- 4005
- HGNC
- 4005
- UniProt
- P25791
- Pathways
- Chromatin Binding
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